INT208264

Context Info Confidence 0.16 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 1.16 Pain Relevance 0.15

mitochondrion (Park7, Pten) cytoplasm (Park7, Pten) nucleus (Park7, Pten) aging (Pten) intracellular (Pten) mitochondrion organization (Park7)

Park7 (Rattus norvegicus) Pten (Rattus norvegicus)

Pain Link Frequency Relevance Heat Inflammation 6 91.36 fibrosis 10 42.16 anesthesia 2 5.00 imagery 2 5.00

Disease Link Frequency Relevance Heat Cancer 26 100.00 INFLAMMATION 6 91.36 Acquired Immune Deficiency Syndrome Or Hiv Infection 2 83.60 Pulmonary Fibrosis 6 43.84 Shock 2 18.60 Asthma 10 5.00 Fibrosis 4 5.00 Overdose 2 5.00 Parkinson's Disease 2 5.00 Hypoxia 2 5.00

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Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

DJ-1/PARK7, a negative regulator of the tumor suppressor PTEN and promoter of proliferative pathways and cell survival [53,54], was increased (>30-fold) at 24 hours.

DJ-1 Negative_regulation (regulator) of PTEN associated with cancer

1) Confidence 0.16 Published 2007 Journal Respir Res Section Body Doc Link PMC1876226 Disease Relevance 0.58 Pain Relevance 0.08

DJ-1/PARK7, a negative regulator of the tumor suppressor PTEN and promoter of proliferative pathways and cell survival [53,54], was increased (>30-fold) at 24 hours.

PARK7 Negative_regulation (regulator) of PTEN associated with cancer

2) Confidence 0.07 Published 2007 Journal Respir Res Section Body Doc Link PMC1876226 Disease Relevance 0.58 Pain Relevance 0.08

General Comments

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