INT208282

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 1.02
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Vcan) extracellular region (Vcan) cell adhesion (Vcan)
proteinaceous extracellular matrix (Vcan)
Anatomy Link Frequency
frontal cortex 1
Vcan (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Dopamine 35 63.12 Quite High
gABA 16 5.00 Very Low Very Low Very Low
Locus ceruleus 10 5.00 Very Low Very Low Very Low
midbrain 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
fibrosis 5 5.00 Very Low Very Low Very Low
Somatostatin 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 5 5.00 Very Low Very Low Very Low
Hippocampus 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Urological Neuroanatomy 4 99.68 Very High Very High Very High
Cancer 13 99.42 Very High Very High Very High
Schizophrenia 220 92.32 High High
Congenital Anomalies 44 83.92 Quite High
Galactorrhea 4 64.80 Quite High
Suicidal Behaviour 2 55.84 Quite High
Stress 14 29.16 Quite Low
Disease 27 5.00 Very Low Very Low Very Low
Apoptosis 13 5.00 Very Low Very Low Very Low
Attention Deficit Hyperactivity Disorder 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Drosophila protein J-1/Parkinson protein 7 (DJ-1/PARK7), a negative regulator of PTEN tumor suppressor and a potential prognostic marker for cancer, was increased by >30-fold at 24 hours and the tumor suppressor-related protein, hyaluronate binding protein-1 (HABP-1), was increased >15 fold (Fig. 4D and Table 1) while transgelin (TAGLN2), was the most significantly down-regulated protein at >14-fold (Fig. 4D and Table 2).
Positive_regulation (increased) of hyaluronate binding protein-1 associated with cancer
1) Confidence 0.13 Published 2007 Journal Respir Res Section Body Doc Link PMC1876226 Disease Relevance 0.30 Pain Relevance 0
BPA injection of only female rats causes dose-dependent increases in PG receptor cells in the preoptic and ventromedial areas of the hypothalamus.146,147 BPA also increases PG receptor mRNA in the frontal cortex of ovariectomized female rats.148

Luteinizing Hormone and Testosterone.

Positive_regulation (increases) of PG receptor mRNA in frontal cortex associated with urological neuroanatomy
2) Confidence 0.01 Published 2009 Journal Schizophrenia Bulletin Section Body Doc Link PMC2643957 Disease Relevance 0.72 Pain Relevance 0.03

General Comments

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