INT208353

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.00
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 2.56
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Apoc4, Apoc3) extracellular region (Apoc4, Apoc3) enzyme regulator activity (Apoc3)
lipid binding (Apoc3) extracellular space (Apoc3)
Anatomy Link Frequency
covering 1
Apoc4 (Mus musculus)
Apoc3 (Mus musculus)
Pain Link Frequency Relevance Heat
addiction 9 82.64 Quite High
Central nervous system 24 49.40 Quite Low
anesthesia 3 5.00 Very Low Very Low Very Low
Immobilon 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 279 100.00 Very High Very High Very High
Disease 15 36.04 Quite Low
Targeted Disruption 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As shown previously [24], our data confirm that more apoE4 molecules are associated with HDL or EM than apoE3 (Table 1).
apoE4 Binding (associated) of apoE3 associated with disorder of lipid metabolism
1) Confidence 0.00 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 1.04 Pain Relevance 0
We also found that more apoE4 molecules are associated with HDL or EM than apoE3.
apoE4 Binding (associated) of apoE3 associated with disorder of lipid metabolism
2) Confidence 0.00 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 0.69 Pain Relevance 0.04
Here we show that apoE3-HDL induces a strong cholesterol release, while apoE4-HDL induces a very weak release, and that this isoform-specific effect of apoE associated with lipid particle (HDL or EM) is due to the finding that (1) apoE4 has a higher affinity to lipid particles and thus a greater number of apoE4 molecules bind to lipid particles than apoE3, and (2) with increasing number of apoE molecules covering the surface of lipid particle, both apoE3 and apoE4 inhibit the lipid-particle-mediated cholesterol release.
apoE4 Binding (bind) of apoE3 in covering associated with disorder of lipid metabolism
3) Confidence 0.00 Published 2007 Journal Mol Neurodegener Section Body Doc Link PMC1876452 Disease Relevance 0.84 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox