INT208458

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.19
Pain Relevance 0.15

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (Bdnf) cytoplasmic membrane-bounded vesicle (Bdnf) nucleus (TWIST1)
DNA binding (TWIST1) transcription factor binding (TWIST1)
Anatomy Link Frequency
extracellular matrix 2
TWIST1 (Homo sapiens)
Bdnf (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Nerve growth factor 5 100.00 Very High Very High Very High
Spinal cord 75 91.44 High High
Sciatic nerve 1 16.48 Low Low
medulla 4 5.00 Very Low Very Low Very Low
Calcitonin gene-related peptide 3 5.00 Very Low Very Low Very Low
cerebral cortex 2 5.00 Very Low Very Low Very Low
cva 2 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Inflammation 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 3 100.00 Very High Very High Very High
Spinal Cord Injury 55 91.72 High High
Injury 42 41.48 Quite Low
Cicatrix 13 5.00 Very Low Very Low Very Low
Heart Rate Under Development 7 5.00 Very Low Very Low Very Low
INFLAMMATION 4 5.00 Very Low Very Low Very Low
Gliosis 4 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Contusions 2 5.00 Very Low Very Low Very Low
Neurodegenerative Disease 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SCs promote axonal regeneration by secretion of adhesion molecules such as L1 and N-CAM, extracellular matrix molecules such as collagen [72] and laminin (see Chernousov and Carey [73] for review), and a number of trophic factors such as FGF-2 [74], nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and NT3 (see Mirsky et al [75] for review).
SCs Positive_regulation (promote) of Localization (secretion) of BDNF in extracellular matrix associated with nerve growth factor and adhesions
1) Confidence 0.01 Published 2007 Journal J Neuroengineering Rehabil Section Body Doc Link PMC1876804 Disease Relevance 0.19 Pain Relevance 0.15

General Comments

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