INT208468

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 2.30
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (IL16) extracellular region (IL16) plasma membrane (IL16)
nucleus (IL16) intracellular (IL16) cytoplasm (IL16)
Anatomy Link Frequency
macrophages 1
IL16 (Homo sapiens)
Pain Link Frequency Relevance Heat
Crohn's disease 7 87.08 High High
Inflammation 39 77.84 Quite High
rheumatoid arthritis 1 75.72 Quite High
COX2 3 67.92 Quite High
Inflammatory response 6 5.00 Very Low Very Low Very Low
cytokine 4 5.00 Very Low Very Low Very Low
fibrosis 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 101 99.54 Very High Very High Very High
Stomach Cancer 1 99.16 Very High Very High Very High
Inflammatory Bowel Disease 10 86.32 High High
Esophageal Disease 36 84.84 Quite High
Rheumatoid Arthritis 1 75.72 Quite High
Asthma 1 74.72 Quite High
Immune System Diseases 1 72.92 Quite High
INFLAMMATION 41 66.16 Quite High
Non-small-cell Lung Cancer 8 63.16 Quite High
Pneumonia 36 61.60 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Gao et al. demonstrated that IL16:rs11556218 was significantly associated with colorectal and gastric cancer, but did not observe a correlation between IL16 serum levels measured in these patients and rs11556218 [21].
IL16 Binding (associated) of associated with stomach cancer
1) Confidence 0.42 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2928273 Disease Relevance 0.72 Pain Relevance 0.13
Conversely, circulating IL-16 was increased in patients with WD (our results) and is produced by macrophages isolated from blood [16], but the expression of IL-16 is not increased in macrophages infiltrating intestinal lesions of one patient with WD [15], suggesting that IL-16 is associated with the systemic phase of WD.
IL-16 Binding (associated) of in macrophages associated with disease
2) Confidence 0.34 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1876813 Disease Relevance 1.58 Pain Relevance 0.16

General Comments

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