INT208524

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 7
Total Number 8
Disease Relevance 3.22
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (PTPRC)
Anatomy Link Frequency
sputum 1
glands 1
PTPRC (Homo sapiens)
Pain Link Frequency Relevance Heat
Arthritis 44 78.32 Quite High
cytokine 65 57.80 Quite High
chemokine 7 54.16 Quite High
Inflammation 95 50.00 Quite Low
headache 1 23.48 Low Low
Pain 7 21.60 Low Low
rheumatoid arthritis 11 10.80 Low Low
COX2 4 5.76 Low Low
corticosteroid 12 5.00 Very Low Very Low Very Low
Inflammatory stimuli 10 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 13 99.32 Very High Very High Very High
Bronchitis 7 97.00 Very High Very High Very High
Reprotox - General 1 7 96.36 Very High Very High Very High
Rheumatoid Arthritis 19 95.68 Very High Very High Very High
Flushing 1 94.80 High High
Bacterial Infection 1 92.96 High High
Cancer 108 90.08 High High
Chronic Fatigue Syndrome 65 88.44 High High
Sprains And Strains 17 88.24 High High
Togavirus Infection 23 84.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
blockers induced a significant down-regulation in CD45 (1157.0 ± 712.9 and 545.8 ± 253.2, P = 0.007) and CD3 (402.8 ± 203.0 and 224.8 ± 107.7, P = 0.039) ST expression.


Regulation (regulation) of CD45
1) Confidence 0.11 Published 2010 Journal Arthritis Res Ther Section Body Doc Link PMC2945042 Disease Relevance 0.21 Pain Relevance 0.13
Co-culture with BMMSCs results in a transient up regulation of CD45RO levels at 24 hr with 1% BMMSCs and with IFN?
Regulation (regulation) of CD45RO
2) Confidence 0.10 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2814860 Disease Relevance 0.06 Pain Relevance 0
A cross tabulation of the empiric classification and LCA classification is presented in Table 2.
Regulation (tabulation) of LCA
3) Confidence 0.05 Published 2008 Journal Behav Brain Funct Section Body Doc Link PMC2569951 Disease Relevance 0.65 Pain Relevance 0
Similarly, the concentrations of MUC-1, a progesterone-dependent glycoprotein secreted by the glands, are lower at day LH + 10 in women suffering recurrent spontaneous miscarriage than in fertile controls [55].
Regulation (concentrations) of glycoprotein in glands associated with reprotox - general 1
4) Confidence 0.03 Published 2007 Journal Placenta Section Body Doc Link PMC1878510 Disease Relevance 0.25 Pain Relevance 0.03
This effect is probably due to the alterations in glycoprotein composition of sputum (Braga et al 1985).
Spec (probably) Regulation (alterations) of glycoprotein in sputum
5) Confidence 0.01 Published 2008 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2650606 Disease Relevance 0.33 Pain Relevance 0
This difference can only be attributed to the vector backbone, as the glycoprotein which is responsible for virus entry into the cell was the same for the retroviral and one of the lentivral vectors applied (LCMV-GP).
Regulation (responsible) of glycoprotein
6) Confidence 0.01 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2707627 Disease Relevance 0.64 Pain Relevance 0
The glycoprotein is then further modified and disulfide bonded in the ER, translocated to the Golgi, and cleaved to form the mature alpha and beta disulfide linked chains in the trans Golgi [12].
Regulation (modified) of glycoprotein
7) Confidence 0.01 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2856549 Disease Relevance 0.29 Pain Relevance 0
In particular, changes in the viral envelope glycoprotein E1 were observed, potentially affecting viral fusion, assembly, and/or tropism.
Regulation (changes) of glycoprotein E1
8) Confidence 0.00 Published 2007 Journal PLoS Pathogens Section Body Doc Link PMC1904475 Disease Relevance 0.79 Pain Relevance 0

General Comments

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