INT208555

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.77
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.02
Pain Relevance 0.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (YWHAQ, Atxn1) cytoplasm (YWHAQ, Atxn1) nucleoplasm (Atxn1)
RNA binding (Atxn1) protein targeting (YWHAQ) nucleolus (YWHAQ)
YWHAQ (Homo sapiens)
Atxn1 (Mus musculus)
Pain Link Frequency Relevance Heat
anesthesia 1 83.60 Quite High
Pyramidal cell 9 5.00 Very Low Very Low Very Low
Hippocampus 4 5.00 Very Low Very Low Very Low
Glutamate 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
long-term potentiation 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
amygdala 1 5.00 Very Low Very Low Very Low
excitatory amino acid 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 12 98.36 Very High Very High Very High
Disease 30 91.04 High High
Spinocerebellar Ataxia Type 2 47 86.16 High High
Frailty 4 78.52 Quite High
Cognitive Disorder 9 72.88 Quite High
Neurodegenerative Disease 7 65.08 Quite High
Anxiety Disorder 12 5.00 Very Low Very Low Very Low
Toxicity 5 5.00 Very Low Very Low Very Low
Tremor 5 5.00 Very Low Very Low Very Low
Huntington's Chorea 5 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Emamian et al. [7] demonstrated that serine 776 (S776) in ataxin 1 (ATXN1) is essential for its pathogenicity in transgenic mice; Chen et al. [8] showed that phosphorylation of this residue by Akt enables 14-3-3 to interact with and stabilize ATXN1.
14-3-3 Positive_regulation (stabilize) of ATXN1 associated with targeted disruption
1) Confidence 0.77 Published 2007 Journal PLoS Medicine Section Body Doc Link PMC1880853 Disease Relevance 1.02 Pain Relevance 0.08

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox