INT208776

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Context Info
Confidence 0.49
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.02
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

small molecule metabolic process (GNB3) plasma membrane (GNB3) GTPase activity (GNB3)
signal transducer activity (GNB3)
GNB3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Serotonin 39 97.84 Very High Very High Very High
addiction 3 61.80 Quite High
Nicotine 3 61.36 Quite High
Dopamine 9 5.00 Very Low Very Low Very Low
dopamine receptor 6 5.00 Very Low Very Low Very Low
Triptan 3 5.00 Very Low Very Low Very Low
depression 3 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
Hippocampus 3 5.00 Very Low Very Low Very Low
Raphe 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Schizophrenia 108 96.48 Very High Very High Very High
Stress 15 71.12 Quite High
Nicotine Addiction 3 61.80 Quite High
Disease 9 41.68 Quite Low
Mental Disorders 15 5.00 Very Low Very Low Very Low
Psychosis 6 5.00 Very Low Very Low Very Low
Syndrome 3 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 3 5.00 Very Low Very Low Very Low
Depression 3 5.00 Very Low Very Low Very Low
Weight Gain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
GNB3: G-protein beta-3 subunit gene

Competing interests

Positive_regulation (interests) of Gene_expression (interests) of G-protein beta-3 subunit
1) Confidence 0.49 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC1888684 Disease Relevance 0.26 Pain Relevance 0.07
GNB3: G-protein beta-3 subunit gene

Competing interests

Positive_regulation (interests) of Gene_expression (interests) of GNB3
2) Confidence 0.49 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC1888684 Disease Relevance 0.26 Pain Relevance 0.07
However, no association between antipsychotic medication response and the occurrence of T-allele, which has been reported to have a GNB3 expression increasing effect [21] was found in this study.


Positive_regulation (increasing) of Gene_expression (expression) of GNB3
3) Confidence 0.46 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC1888684 Disease Relevance 0.50 Pain Relevance 0.16

General Comments

This test has worked.

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