INT208919

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Context Info
Confidence 0.09
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.73
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Fli1) DNA binding (Fli1)
Anatomy Link Frequency
GCT 1
Fli1 (Mus musculus)
Pain Link Frequency Relevance Heat
Serotonin 1 98.84 Very High Very High Very High
Inflammation 28 73.52 Quite High
substance P 22 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 12 99.20 Very High Very High Very High
Shock 2 93.02 High High
Adhesions 1 87.28 High High
Apoptosis 3 85.98 High High
INFLAMMATION 33 73.52 Quite High
Death 3 63.92 Quite High
Primitive Neuroectodermal Tumors 27 50.00 Quite Low
Sarcoma 27 50.00 Quite Low
Malignant Neoplastic Disease 3 30.56 Quite Low
Lymphadenopathy 3 27.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
l from the reaction was PCR amplified using EWS 22.3 forward primer (5'-TCC TAC AGC CAA GCT CCA AGT C-3') and FLI1 11.3 reverse primer (5'-ACT CCC CGT TGG TCC CCT CC-3') in a 20-?
Regulation (using) of FLI1 in GCT
1) Confidence 0.09 Published 2010 Journal J Med Case Reports Section Body Doc Link PMC2848680 Disease Relevance 0 Pain Relevance 0
Overall NK1R-dependent genes were classified following the biological processes with which they are involved (GO anthology): apoptosis (GZMA, TNFRSF1B, TNFRSF1A, TRAF3, NOS2A, and BID); cell adhesion/hyaluronic acid binding (CD44 and AGC1); cell cycle (CCND2 and CCNG1); cell-cell signaling (FGF11 and GJA7); cytokinesis (CDC42 and KIF1B); development (FMR2); extracellular transporters & carriers (APOE); G-protein coupled receptors (GNA13 and PTGIR); growth factors (MXD1); heat shock proteins (PRNP, HSPH1, and HSPD1); immune response (BST-1, CTSW, and IL1R1); interferons (INFGR1) intracellular kinases (WBP6); intracellular transducers (MAP3K7); kinase activators & inhibitors (YWHAH); membrane channels (KCNAB1, KCNJ12, KCNQ1, and SLC30A4); nucleotide metabolism (PCSK1); oncogenes & tumor suppressors (BRCA1, MAP3K8, RET, VIL2, FLI1, MET, NF2, and VEGFR1); receptor mediated endocytosis (DAB2); receptor tyrosine kinase (EPHA2); regulation of transcription (NEUROD6); serotonin biosynthesis (YTPH1); symporters & antiporters (SLC16A1 and SLC1A1); transcription activators & repressors (FOXA1, HSF1, IER2, and NR1H2); and synaptic transmission (GRID1).


Regulation (regulation) of FLI1 associated with cancer, shock, apoptosis, serotonin and adhesions
2) Confidence 0.05 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0.73 Pain Relevance 0.11

General Comments

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