INT208922

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Context Info
Confidence 0.29
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.36
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Nkx2-5) nucleus (Nkx2-5) DNA binding (Nkx2-5)
transcription factor binding (Nkx2-5) cytoplasm (Nkx2-5)
Nkx2-5 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 22 95.28 Very High Very High Very High
Inflammation 28 50.00 Quite Low
Serotonin 1 22.88 Low Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
ketamine 3 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Myocardial Infarction 23 97.20 Very High Very High Very High
Targeted Disruption 5 88.44 High High
INFLAMMATION 33 50.00 Quite Low
Bladder Disease 3 29.20 Quite Low
Cancer 4 15.32 Low Low
Cystitis 15 5.00 Very Low Very Low Very Low
Overactive Bladder 7 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Abnormal Reflex 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine whether activation of NK1R increases the transcriptional activities of NF-kappaB and Nkx-2.5, an EMSA was performed.
Transcription (transcriptional) of Nkx-2.5
1) Confidence 0.29 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0 Pain Relevance 0.10
Lower relative expression of cardiomyogenic transcription factors, such as GATA-4, Nkx2-5, Isl-1, Mef2 and Hand2, was seen in clonal cell culture.
Transcription (transcription) of Nkx2-5
2) Confidence 0.01 Published 2008 Journal PLoS ONE Section Abstract Doc Link PMC2262151 Disease Relevance 0.36 Pain Relevance 0

General Comments

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