INT20893

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Context Info
Confidence 0.23
First Reported 1986
Last Reported 1995
Negated 0
Speculated 0
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.25
Pain Relevance 3.40

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

IGKV1D-39 (Homo sapiens)
Pain Link Frequency Relevance Heat
agonist 3 99.96 Very High Very High Very High
Opioid 5 99.80 Very High Very High Very High
Enkephalin 37 98.80 Very High Very High Very High
narcan 1 96.48 Very High Very High Very High
antagonist 1 96.12 Very High Very High Very High
Potency 1 83.60 Quite High
opioid receptor 3 75.92 Quite High
Disease Link Frequency Relevance Heat
Disease 1 84.80 Quite High
Adult Respiratory Distress Syndrome 2 84.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Both opioid peptides stimulated O2- release by PMN from donors with low baseline reactivity in a concentration-dependent manner.
Positive_regulation (stimulated) of Localization (release) of O2 associated with opioid
1) Confidence 0.23 Published 1990 Journal Brain Behav. Immun. Section Abstract Doc Link 2159354 Disease Relevance 0 Pain Relevance 0.55
Leu-enkephalin induced baseline reactivity was dependent upon progressive increase in the magnitude of change on O2- release (i.e., the higher the baseline the higher the magnitude of change in O2- generation).
Positive_regulation (increase) of Localization (release) of O2 associated with enkephalin
2) Confidence 0.23 Published 1990 Journal Brain Behav. Immun. Section Abstract Doc Link 2159354 Disease Relevance 0 Pain Relevance 0.92
DADLE (delta receptor agonist) increased O2- release in 10(-11) M concentration, while DAGO (mu receptor agonist) had no effect in any concentration examined.
Positive_regulation (increased) of Localization (release) of O2 associated with agonist
3) Confidence 0.19 Published 1995 Journal Neuropeptides Section Abstract Doc Link 8837964 Disease Relevance 0 Pain Relevance 1.25
The Escherichia coli product, N-formyl methionyl leucyl phenylalanine (FMLP), was employed to stimulate O-2 release.
Positive_regulation (stimulate) of Localization (release) of O-2
4) Confidence 0.10 Published 1986 Journal J. Surg. Res. Section Abstract Doc Link 3023754 Disease Relevance 0.25 Pain Relevance 0.68

General Comments

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