INT208938

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tacr1, Nkx2-5) cell differentiation (Nkx2-5) signal transduction (Tacr1)
nucleus (Nkx2-5) plasma membrane (Tacr1) DNA binding (Nkx2-5)
Tacr1 (Mus musculus)
Nkx2-5 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 22 96.36 Very High Very High Very High
Inflammation 28 50.00 Quite Low
Serotonin 1 24.20 Low Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 33 50.00 Quite Low
Bladder Disease 3 29.20 Quite Low
Cancer 4 16.64 Low Low
Cystitis 15 5.00 Very Low Very Low Very Low
Overactive Bladder 7 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Abnormal Reflex 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine whether activation of NK1R increases the transcriptional activities of NF-kappaB and Nkx-2.5, an EMSA was performed.
Spec (27305) Positive_regulation (activation) of NK1R Spec (whether) Positive_regulation (increases) of Nkx-2.5
1) Confidence 0.17 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0 Pain Relevance 0.10

General Comments

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