INT208939

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Context Info
Confidence 0.19
First Reported 2007
Last Reported 2007
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.10

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Tacr1, Nfkb1) signal transduction (Tacr1, Nfkb1) mitochondrion (Nfkb1)
DNA binding (Nfkb1) protein complex (Nfkb1) signal transducer activity (Tacr1)
Tacr1 (Mus musculus)
Nfkb1 (Mus musculus)
Pain Link Frequency Relevance Heat
substance P 22 96.36 Very High Very High Very High
Inflammation 28 50.00 Quite Low
Serotonin 1 24.20 Low Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammatory response 4 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 33 50.00 Quite Low
Bladder Disease 3 28.24 Quite Low
Cancer 4 16.64 Low Low
Cystitis 15 5.00 Very Low Very Low Very Low
Overactive Bladder 7 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Apoptosis 3 5.00 Very Low Very Low Very Low
Abnormal Reflex 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To determine whether activation of NK1R increases the transcriptional activities of NF-kappaB and Nkx-2.5, an EMSA was performed.
Spec (27305) Positive_regulation (activation) of NK1R Spec (whether) Positive_regulation (increases) of NF-kappaB
1) Confidence 0.19 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0 Pain Relevance 0.10

General Comments

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