INT208942

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.42
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Mapk14, Jun) nucleus (Mapk14, Jun) mitochondrion (Mapk14)
cell morphogenesis (Mapk14) DNA binding (Jun) response to stress (Mapk14)
Mapk14 (Mus musculus)
Jun (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 28 99.04 Very High Very High Very High
substance P 22 88.20 High High
Inflammatory response 4 87.96 High High
antagonist 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 33 99.04 Very High Very High Very High
Cystitis 15 83.52 Quite High
Bladder Cancer 1 72.96 Quite High
Bladder Disease 3 38.16 Quite Low
Diabetes Mellitus 1 6.88 Low Low
Overactive Bladder 7 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Cancer 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is known that the activation of MAPK (JNK, p38) and NF-kappaB signaling pathways leads to the activation of AP-1 and, consequently, the inflammation [49].
Positive_regulation (activation) of p38 Positive_regulation (leads) of Positive_regulation (activation) of AP-1 associated with inflammation
1) Confidence 0.10 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0.42 Pain Relevance 0.20

General Comments

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