INT208945

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.33
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nkx2-5, Nppa) cytoplasm (Nkx2-5, Nppa) cell differentiation (Nkx2-5)
DNA binding (Nkx2-5) transcription factor binding (Nkx2-5)
Anatomy Link Frequency
brain 2
Nkx2-5 (Mus musculus)
Nppa (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 28 56.40 Quite High
substance P 22 52.12 Quite High
Inflammatory response 4 9.16 Low Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
interstitial cystitis 2 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Natriuresis 2 100.00 Very High Very High Very High
Diabetes Mellitus 1 71.84 Quite High
INFLAMMATION 33 56.40 Quite High
Bladder Cancer 1 39.04 Quite Low
Cystitis 15 33.52 Quite Low
Cancer 4 32.40 Quite Low
Overactive Bladder 7 5.00 Very Low Very Low Very Low
Edema 6 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, more recently it was shown that Nkx-2.5 is required for the expression of atrial natriuretic peptide [61] and, along with NF-kappaB, is part of the brain natriuretic peptide promoter [62].
Nkx-2.5 Positive_regulation (required) of Gene_expression (expression) of atrial natriuretic peptide in brain associated with natriuresis
1) Confidence 0.03 Published 2007 Journal BMC Urol Section Body Doc Link PMC1888709 Disease Relevance 0.33 Pain Relevance 0.05

General Comments

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