INT208974

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.12
Pain Relevance 1.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Chi3l1) extracellular region (Chi3l1) endoplasmic reticulum (Chi3l1)
carbohydrate metabolic process (Chi3l1) molecular_function (Chi3l1) cytoplasm (Chi3l1)
Chi3l1 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
antagonist 44 100.00 Very High Very High Very High
qutenza 54 86.72 High High
Potency 4 74.56 Quite High
Endep 20 73.80 Quite High
carbamazepine 4 71.72 Quite High
backache 2 60.00 Quite High
antidepressant 4 53.56 Quite High
Pain 48 50.00 Quite Low
wide dynamic range 8 33.44 Quite Low
Dorsal horn neuron 16 30.88 Quite Low
Disease Link Frequency Relevance Heat
Low Back Pain 2 60.00 Quite High
Pain 46 50.00 Quite Low
Nociception 16 49.20 Quite Low
Inflammatory Pain 10 5.00 Very Low Very Low Very Low
Psychosis 6 5.00 Very Low Very Low Very Low
Hyperalgesia 4 5.00 Very Low Very Low Very Low
Death 4 5.00 Very Low Very Low Very Low
Neuropathic Pain 4 5.00 Very Low Very Low Very Low
Cancer Pain 4 5.00 Very Low Very Low Very Low
Neuralgia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
SB 290157, a selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor, CGP-37157, a cell-permeable benzodiazepine inhibitor of mitochondrial Na+/Ca2+ exchanger, and flunarizine, a piperazine derivative blocker of T-type cardiac Ca2+ channels were included in assays in DRG cultures.
Negative_regulation (antagonist) of CGP-37157 associated with antagonist
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1890308 Disease Relevance 0.06 Pain Relevance 0.59
SB 290157, a selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor, CGP-37157, a cell-permeable benzodiazepine inhibitor of mitochondrial Na+/Ca2+ exchanger, and flunarizine, a piperazine derivative blocker of T-type cardiac Ca2+ channels were included in assays in DRG cultures.
Negative_regulation (inhibitor) of CGP-37157 associated with antagonist
2) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1890308 Disease Relevance 0.06 Pain Relevance 0.58

General Comments

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