INT208988

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.05

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (Itpr3) endoplasmic reticulum (Itpr3) nucleolus (Itpr3)
nucleus (Itpr3) transmembrane transport (Itpr3) cytoplasm (Itpr3)
CALM1 (Homo sapiens)
Itpr3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
TRP channel 6 97.24 Very High Very High Very High
Pain 24 50.00 Quite Low
qutenza 27 5.00 Very Low Very Low Very Low
antagonist 22 5.00 Very Low Very Low Very Low
Endep 10 5.00 Very Low Very Low Very Low
Dorsal horn neuron 8 5.00 Very Low Very Low Very Low
agonist 7 5.00 Very Low Very Low Very Low
IPN 5 5.00 Very Low Very Low Very Low
Analgesic 5 5.00 Very Low Very Low Very Low
wide dynamic range 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 1 75.72 Quite High
Death 2 74.24 Quite High
Pain 23 50.00 Quite Low
Nociception 8 5.00 Very Low Very Low Very Low
Inflammatory Pain 5 5.00 Very Low Very Low Very Low
Psychosis 3 5.00 Very Low Very Low Very Low
Hyperalgesia 2 5.00 Very Low Very Low Very Low
Neuropathic Pain 2 5.00 Very Low Very Low Very Low
Cancer Pain 2 5.00 Very Low Very Low Very Low
Neuralgia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
However, both Ca2+- calmodulin and cytoplasmic domain of IP3RER competes for an overlapping site and either open or close the given TRP channel, respectively and the preference only depends on the levels of [Ca2+]i.
calmodulin Binding (domain) of IP3RER associated with trp channel
1) Confidence 0.01 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1890308 Disease Relevance 0.15 Pain Relevance 0.05

General Comments

This test has worked.

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