INT209108

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Context Info
Confidence 0.33
First Reported 2006
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 6
Total Number 6
Disease Relevance 1.72
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (GOPC) plasma membrane (GOPC) cytoplasm (GOPC)
Anatomy Link Frequency
sperm cells 2
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 35 96.72 Very High Very High Very High
agonist 36 96.28 Very High Very High Very High
Spinal cord 17 88.64 High High
Glutamate 54 75.60 Quite High
Central nervous system 22 59.12 Quite High
Glutamate receptor 4 53.40 Quite High
opioid receptor 10 50.00 Quite Low
excitatory amino acid 2 43.76 Quite Low
Inflammatory response 2 38.36 Quite Low
Inflammation 20 37.12 Quite Low
Disease Link Frequency Relevance Heat
Neuromyelitis Optica 87 99.42 Very High Very High Very High
Osteoporosis 46 93.44 High High
Targeted Disruption 9 77.68 Quite High
Multiple Myeloma 22 50.00 Quite Low
Sperm Disorder 8 50.00 Quite Low
INFLAMMATION 25 38.00 Quite Low
Autoimmune Disease 3 34.88 Quite Low
Hypercalcemia 9 30.56 Quite Low
Spinal Cord Compression 2 12.36 Low Low
Demyelinating Disease 15 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hospital revenues, at least in the US seem to have compensated for the loss of revenue caused by the shift to ambulatory surgery (Fig 3).45,50,51

POLITICS AND FINANCE

Positive_regulation (compensated) of Negative_regulation (loss) of Fig
1) Confidence 0.33 Published 2006 Journal Ulster Med J Section Body Doc Link PMC1891798 Disease Relevance 0 Pain Relevance 0
Treatment with bortezomib resulted in a fivefold increase in levels of osteopontin while treatment with the glucocorticoid caused a strong reduction of osteopontin (Fig. 4D).
Positive_regulation (caused) of Negative_regulation (reduction) of Fig
2) Confidence 0.24 Published 2010 Journal European Journal of Haematology Section Body Doc Link PMC2970902 Disease Relevance 0.70 Pain Relevance 0
Naltrindole at 10-4 M (p < 0.05) and 10-5 M (p < 0.01) induces a statistical significant decrease of the percent of sperm cells with active mitochondria (Fig. 4, Panel D).
Positive_regulation (induces) of Negative_regulation (decrease) of Fig in sperm cells
3) Confidence 0.20 Published 2010 Journal Reprod Biol Endocrinol Section Body Doc Link PMC2901311 Disease Relevance 0 Pain Relevance 0.17
Stimulation of 1° h.AoSMCs also led to rapid F-actin polymerization (Fig. 6B) and cofilin phosphorylation with optimal responses generated using 1 ?
Positive_regulation (led) of Negative_regulation (polymerization) of Fig
4) Confidence 0.12 Published 2008 Journal Cellular Signalling Section Body Doc Link PMC2681257 Disease Relevance 0 Pain Relevance 0.11
Serum containing NMO-IgG, but not control serum, induced rapid down-regulation of surface AQP4 (Fig. 1 A).
Positive_regulation (induced) of Negative_regulation (regulation) of Fig associated with neuromyelitis optica
5) Confidence 0.07 Published 2008 Journal The Journal of Experimental Medicine Section Body Doc Link PMC2571922 Disease Relevance 1.02 Pain Relevance 0.22
When human MPGES1 was mutated at these three positions toward the corresponding rat residues (triple mutant hum T131V,L135F,A138F), the enzyme became unresponsive to the inhibitor (Fig. 4B).
Positive_regulation (unresponsive) of Negative_regulation (inhibitor) of Fig
6) Confidence 0.05 Published 2010 Journal The Journal of Biological Chemistry Section Body Doc Link PMC2937957 Disease Relevance 0 Pain Relevance 0

General Comments

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