INT209139

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Context Info
Confidence 0.61
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.28
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (PDE4A) signal transduction (PDE4A) plasma membrane (PDE4A)
nucleus (PDE4A) cytoplasm (PDE4A)
PDE4A (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 16 76.44 Quite High
agonist 5 14.32 Low Low
cytokine 5 5.00 Very Low Very Low Very Low
Inflammatory mediators 1 5.00 Very Low Very Low Very Low
Inflammatory response 1 5.00 Very Low Very Low Very Low
Dismenorea 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 18 76.44 Quite High
Hypertension 2 70.52 Quite High
Reprotox - General 2 2 69.40 Quite High
Heart Disease 1 68.52 Quite High
Premature Birth 9 5.00 Very Low Very Low Very Low
Dysmenorrhea 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Conversely, cAMP- and hormonal-sensitive promoters control the transcription of some of the PDE4 short-forms, leading to a decrease in cAMP levels after a sustained elevation of the cyclic nucleotide content.
Regulation (control) of Transcription (transcription) of PDE4
1) Confidence 0.61 Published 2007 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC1892053 Disease Relevance 0.28 Pain Relevance 0.04

General Comments

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