INT209180

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Context Info
Confidence 0.47
First Reported 2007
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.09
Pain Relevance 0.39

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (ABCA1) small molecule metabolic process (ABCA1) Golgi apparatus (ABCA1)
ATPase activity (ABCA1) plasma membrane (ABCA1) intracellular (ABCA1)
Anatomy Link Frequency
myometrium 1
body 1
ABCA1 (Homo sapiens)
Pain Link Frequency Relevance Heat
metalloproteinase 48 100.00 Very High Very High Very High
chemokine 4 51.44 Quite High
cytokine 3 50.48 Quite High
withdrawal 3 27.08 Quite Low
Inflammation 19 25.52 Quite Low
rheumatoid arthritis 7 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
Dismenorea 5 5.00 Very Low Very Low Very Low
agonist 5 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Renal Cancer 39 98.60 Very High Very High Very High
Cancer 101 93.56 High High
Obesity 51 84.56 Quite High
Skin Cancer 6 73.28 Quite High
Targeted Disruption 1 67.52 Quite High
Malignant Neoplastic Disease 7 64.92 Quite High
Disease 11 26.80 Quite Low
INFLAMMATION 19 25.52 Quite Low
Solid Tumor 3 15.92 Low Low
Carcinoma 7 8.08 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Treatment of the cells with apoA-I does not lead to a simultaneous increase in ABCA1 transcription (panel B).


Transcription (transcription) of ABCA1
1) Confidence 0.47 Published 2010 Journal Lipids Health Dis Section Body Doc Link PMC2917427 Disease Relevance 0.22 Pain Relevance 0
DPP IV has been commonly described as a membrane-bound peptidase, but the expression and activity of soluble isoforms have been reported in body fluids and in cytosolic fractions [6,37,38].
Transcription (described) of membrane-bound in body
2) Confidence 0.12 Published 2010 Journal BMC Cancer Section Body Doc Link PMC2876082 Disease Relevance 0.81 Pain Relevance 0
A new approach to our understanding of progesterone function has followed the description of membrane-bound isoforms of the PGR (mPGR) resembling GPCRs in human myometrium [29,30].
Transcription (description) of membrane-bound in myometrium
3) Confidence 0.04 Published 2007 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC1892059 Disease Relevance 0.07 Pain Relevance 0
Expression of membrane-bound MMPs is differentially controlled at the transcriptional level [63, 65, 66].
Transcription (at) of membrane associated with metalloproteinase
4) Confidence 0.03 Published 2011 Journal Biochemistry Research International Section Body Doc Link PMC2989751 Disease Relevance 0 Pain Relevance 0.39

General Comments

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