INT209226

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Context Info
Confidence 0.31
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.34

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Psd) intracellular (Psd) cytoplasm (Psd)
Anatomy Link Frequency
chromaffin cells 1
Psd (Mus musculus)
Pain Link Frequency Relevance Heat
Catecholamine 10 100.00 Very High Very High Very High
long-term potentiation 54 79.60 Quite High
Neurobehavioral 2 73.76 Quite High
Hippocampus 20 64.00 Quite High
Pyramidal cell 4 53.48 Quite High
nMDA receptor 19 5.00 Very Low Very Low Very Low
Glutamate receptor 6 5.00 Very Low Very Low Very Low
Neurotransmitter 5 5.00 Very Low Very Low Very Low
Central nervous system 3 5.00 Very Low Very Low Very Low
Glutamate 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pheochromocytoma 16 88.88 High High
Congenital Anomalies 6 45.96 Quite Low
Body Weight 3 41.92 Quite Low
Cognitive Disorder 8 5.00 Very Low Very Low Very Low
Toxicity 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Convulsion 2 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Drug Induced Neurotoxicity 2 5.00 Very Low Very Low Very Low
Decapitation 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These findings indicate that Neto1 is required to establish or maintain the normal abundance of NR2A-containing NMDARs in the PSD.
Localization (abundance) of PSD
1) Confidence 0.31 Published 2009 Journal PLoS Biology Section Body Doc Link PMC2652390 Disease Relevance 0 Pain Relevance 0.06
In additional ex vivo experiments, we investigated protein expression levels in the postsynaptic density (PSD) and catecholamine release from chromaffin cells to further reveal underlying mechanisms.
Localization (release) of PSD in chromaffin cells associated with catecholamine
2) Confidence 0.29 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1892123 Disease Relevance 0.09 Pain Relevance 0.28

General Comments

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