INT209310

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Context Info
Confidence 0.16
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.17
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (St13) protein folding (St13) cytosol (St13)
protein complex (St13) cytoplasm (St13)
Anatomy Link Frequency
neuronal 1
hip 1
neurons 1
St13 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Hippocampus 35 100.00 Very High Very High Very High
Osteoarthritis 4 99.04 Very High Very High Very High
spinal dorsal horn 17 98.76 Very High Very High Very High
Nucleus accumbens 6 78.20 Quite High
Pyramidal cell 13 75.56 Quite High
addiction 1 60.88 Quite High
Substantia nigra 1 50.20 Quite High
Spinal cord 11 50.00 Quite Low
interneuron 1 20.76 Low Low
Pain 7 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Frailty 14 99.04 Very High Very High Very High
Urological Neuroanatomy 6 5.00 Very Low Very Low Very Low
Pain 6 5.00 Very Low Very Low Very Low
Premenstrual Syndrome 6 5.00 Very Low Very Low Very Low
Nociception 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Death 3 5.00 Very Low Very Low Very Low
Epilepsy 2 5.00 Very Low Very Low Very Low
Anxiety Disorder 2 5.00 Very Low Very Low Very Low
Hypersensitivity 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Overall, 94% of patients who underwent a hip replacement because of osteoarthritis and this percentage was similar across the prosthesis groups.
Regulation (underwent) of hip in hip associated with osteoarthritis
1) Confidence 0.16 Published 2008 Journal PLoS Medicine Section Body Doc Link PMC2528048 Disease Relevance 0.17 Pain Relevance 0.05
M significantly reduced peak IGly to 95.0 ± 0.8% (P < 0.05 compared with control, n = 4), 85.8 ± 2.2% (P < 0.01 compared with control, n = 5), 80.2 ± 4.0% (P < 0.01 compared with control, n = 5) and 63.4 ± 2.2% (P < 0.001 compared with control, n = 8, Paired Student's t-test for all) of control in HIP neurons, respectively; and in SDH neurons, peak IGly was reduced to 97.0 ± 0.9% (P < 0.05 compared with control, n = 6), 89.1 ± 2.0% (P < 0.01 compared with control, n = 7), 83.1 ± 3.0% (P < 0.01 compared with control, n = 8) and 75.3 ± 2.1% (P < 0.01 compared with control, n = 7, P < 0.01 compared with the inhibition of 10 ?
Regulation (control) of HIP in neurons associated with spinal dorsal horn
2) Confidence 0.10 Published 2009 Journal Mol Pain Section Body Doc Link PMC2651124 Disease Relevance 0 Pain Relevance 0.17
The transport of the TRPC5 channels into the presynaptic terminals and the up-regulation of TRPC4 and 5 protein levels in the HIP of P48 compared to P0 mice suggests that these channels may be involved in neuronal development.
Regulation (regulation) of HIP in neuronal associated with hippocampus
3) Confidence 0.03 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1892805 Disease Relevance 0 Pain Relevance 0.30

General Comments

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