INT20937

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Context Info
Confidence 0.43
First Reported 1990
Last Reported 2009
Negated 1
Speculated 1
Reported most in Abstract
Documents 4
Total Number 4
Disease Relevance 0.62
Pain Relevance 1.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (MGP) extracellular space (MGP) extracellular region (MGP)
endoplasmic reticulum (MGP) proteinaceous extracellular matrix (MGP) protein complex (MGP)
Anatomy Link Frequency
blood 1
MGP (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 7 98.92 Very High Very High Very High
opioid receptor 4 98.48 Very High Very High Very High
Enkephalin 2 98.00 Very High Very High Very High
Codeine 2 95.24 Very High Very High Very High
Kappa opioid receptor 1 85.76 High High
agonist 1 83.36 Quite High
Morphine 1 79.28 Quite High
depression 1 74.64 Quite High
Opioid 3 72.64 Quite High
Myofascial pain syndrome 3 71.68 Quite High
Disease Link Frequency Relevance Heat
Toxicity 12 90.92 High High
Constipation 1 78.00 Quite High
Respiratory Failure 1 75.60 Quite High
Nociception 2 75.00 Quite High
Temporomandibular Joint Disorders 3 71.68 Quite High
Bruxism 1 59.28 Quite High
Calcification 6 5.00 Very Low Very Low Very Low
Vomiting 2 5.00 Very Low Very Low Very Low
Lead Poisoning 2 5.00 Very Low Very Low Very Low
Porphyria 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This study was carried out to examine the effects of MGP gene promoter polymorphism (T-138C) on blood lead levels (BLL) and hematological parameters in 113 battery manufacturing unit workers occupationally exposed to lead and 102 controls.
Spec (examine) Regulation (effects) of MGP in blood
1) Confidence 0.43 Published 2009 Journal Toxicology Mechanisms and Methods Section Abstract Doc Link PMC2736540 Disease Relevance 0.09 Pain Relevance 0
There were no effects of either NTI or OS on clinical outcome measures (anovas: P > 0.194).
Neg (no) Regulation (effects) of NTI
2) Confidence 0.23 Published 2007 Journal J Oral Rehabil Section Abstract Doc Link 17244232 Disease Relevance 0.37 Pain Relevance 0.19
The ED50 values of NTI by intraperitoneal and peroral injections were 104 microg/kg and 1840 microg/kg, respectively, comparable to those of codeine.
Regulation (values) of NTI associated with codeine
3) Confidence 0.11 Published 2008 Journal J. Med. Chem. Section Abstract Doc Link 18637671 Disease Relevance 0.15 Pain Relevance 0.61
Thus, the Ke and Ki values of NTI were 1/530 and 1/90 that of the delta antagonist enkephalin analogue, ICI 174864.
Regulation (values) of NTI associated with antagonist and enkephalin
4) Confidence 0.06 Published 1990 Journal J. Med. Chem. Section Abstract Doc Link 2160538 Disease Relevance 0 Pain Relevance 0.57

General Comments

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