INT209434

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Col1a1) extracellular region (Col1a1) proteinaceous extracellular matrix (Col1a1)
cytoplasm (Col1a1)
Anatomy Link Frequency
urine 2
Col1a1 (Mus musculus)
Pain Link Frequency Relevance Heat
imagery 1 9.60 Low Low
cytokine 4 5.00 Very Low Very Low Very Low
withdrawal 3 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
rheumatoid arthritis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 10 5.00 Very Low Very Low Very Low
Osteopetrosis 6 5.00 Very Low Very Low Very Low
Osteoporosis 3 5.00 Very Low Very Low Very Low
Disease 3 5.00 Very Low Very Low Very Low
Aging 2 5.00 Very Low Very Low Very Low
Postmenopausal Osteoporosis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low
Rheumatoid Arthritis 1 5.00 Very Low Very Low Very Low
Endometriosis (extended) 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This phenotype is mostly due to impairment of osteoclast function, since the number of osteoclasts counted on bone surfaces was similar for all four backgrounds (Figure 4B), while collagen type I degradation products present in the urine of 12-week-old DKO female mice had decreased by 17% compared with WT females (Figure 4C).
Negative_regulation (decreased) of Protein_catabolism (degradation) of collagen type I in urine
1) Confidence 0.10 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1899087 Disease Relevance 0 Pain Relevance 0

General Comments

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