INT209503

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Context Info
Confidence 0.42
First Reported 2007
Last Reported 2010
Negated 0
Speculated 2
Reported most in Body
Documents 3
Total Number 5
Disease Relevance 7.00
Pain Relevance 1.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CADPS) cytosol (CADPS)
Anatomy Link Frequency
platelets 1
CADPS (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammatory response 7 98.48 Very High Very High Very High
Pain 47 92.64 High High
depression 26 88.72 High High
headache 15 88.44 High High
Migraine 8 88.04 High High
Fibrositis 2 86.96 High High
Inflammation 35 85.36 High High
Inflammatory marker 3 80.48 Quite High
Inflammatory stimuli 2 80.12 Quite High
withdrawal 4 77.88 Quite High
Disease Link Frequency Relevance Heat
Syndrome 110 100.00 Very High Very High Very High
Anxiety Disorder 34 99.72 Very High Very High Very High
Cancer 5 99.68 Very High Very High Very High
Post-traumatic Stress Disorder 87 98.44 Very High Very High Very High
INFLAMMATION 38 98.12 Very High Very High Very High
Skin Cancer 1 96.80 Very High Very High Very High
Vertigo 9 96.68 Very High Very High Very High
Breast Cancer 1 96.40 Very High Very High Very High
Adenocarcinoma 1 95.68 Very High Very High Very High
Renal Cancer 1 94.84 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the day of the first exposure, the MAPCEL technicians made a considered judgment as to whether atmospheric conditions were better suited to conducting a CAPs or filtered air exposure, and subjects were randomized accordingly.
Spec (whether) Positive_regulation (conducting) of CAPs
1) Confidence 0.42 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2430224 Disease Relevance 0 Pain Relevance 0.03
The number of circulating platelets increased 2 hr after CAPs exposure, and a similar transient effect on circulating monocytes was present at 6 hr.
Positive_regulation (increased) of CAPs in platelets
2) Confidence 0.39 Published 2008 Journal Environ Health Perspect Section Body Doc Link PMC2430224 Disease Relevance 1.03 Pain Relevance 0.22
The efficacy of canakinumab in the treatment of CAPS provides proof of concept that IL-1?
Positive_regulation (treatment) of CAPS associated with syndrome
3) Confidence 0.32 Published 2010 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2880341 Disease Relevance 0.96 Pain Relevance 0.42
They also had higher CAPS, DTS, anxiety, and disability scores at 1 month.
Positive_regulation (higher) of CAPS associated with anxiety disorder
4) Confidence 0.10 Published 2007 Journal BMC Psychiatry Section Body Doc Link PMC1899490 Disease Relevance 2.48 Pain Relevance 0.33
Notably, in 17 of the above 23 cases, CAPS had been possibly triggered by the cancer; it is very important to realize that thrombotic events associated with aPLs, especially in elder patients, may be the initial and/or single manifestation of the malignant disease.


Spec (possibly) Positive_regulation (triggered) of CAPS associated with malignant neoplastic disease, cancer and disease
5) Confidence 0.08 Published 2007 Journal Yonsei Medical Journal Section Body Doc Link PMC2628175 Disease Relevance 2.55 Pain Relevance 0.11

General Comments

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