INT209527

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.51
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.17
Pain Relevance 0.25

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Muc5ac (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 40 100.00 Very High Very High Very High
cytokine 6 100.00 Very High Very High Very High
Inflammatory mediators 8 96.28 Very High Very High Very High
fibrosis 28 86.12 High High
Inflammatory response 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
COX-2 inhibitor 2 5.00 Very Low Very Low Very Low
anesthesia 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
ketamine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 52 100.00 Very High Very High Very High
Disease 25 99.56 Very High Very High Very High
Nicotine Addiction 1 99.36 Very High Very High Very High
Infection 50 98.72 Very High Very High Very High
Hemophilus Infection 89 98.28 Very High Very High Very High
Injury 9 96.36 Very High Very High Very High
Cystic Fibrosis 28 86.12 High High
Pulmonary Disease 15 85.68 High High
Smoke Inhalation Injury 15 83.04 Quite High
Skin Cancer 1 80.08 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
c-Jun N-terminal kinase (JNK) activation is required for the in vitro transcriptional up-regulation of MUC5AC in response to tobacco smoke [11].
Regulation (regulation) of MUC5AC associated with nicotine addiction
1) Confidence 0.51 Published 2010 Journal Respir Res Section Body Doc Link PMC3014901 Disease Relevance 0.60 Pain Relevance 0.03
Many studies have focused on MUC5AC and MUC2 regulation in airway diseases using mainly airway cell and explant cultures [32-34] while the expression of the oligomeric mucin MUC5B and the membrane-bound mucin MUC4 have not yet been investigated.
Regulation (regulation) of MUC5AC associated with disease
2) Confidence 0.26 Published 2007 Journal Respir Res Section Body Doc Link PMC1899493 Disease Relevance 0.34 Pain Relevance 0.04
While many studies have focused on gene regulation of both MUC2 and MUC5AC using mainly airway cell cultures and explants, regulation of MUC4 and MUC5B in airway diseases have been ignored to date.
Regulation (regulation) of MUC5AC associated with disease
3) Confidence 0.22 Published 2007 Journal Respir Res Section Body Doc Link PMC1899493 Disease Relevance 0.23 Pain Relevance 0.03
Activation of p38 MAPK up-regulates inflammatory cytokines, mucin MUC5AC and down-regulates TLR2 expression while activation of NF-kappa B increases the expression of IL-8, IL-1?
Regulation (regulates) of MUC5AC associated with inflammation and cytokine
4) Confidence 0.21 Published 2008 Journal Respir Res Section Body Doc Link PMC2270828 Disease Relevance 1.00 Pain Relevance 0.15

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox