INT209559

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Context Info
Confidence 0.03
First Reported 2007
Last Reported 2008
Negated 0
Speculated 1
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 4.37
Pain Relevance 2.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Ncoa5) molecular_function (Ncoa5) cellular_component (Ncoa5)
biological_process (Ncoa5)
Ncoa5 (Mus musculus)
Pain Link Frequency Relevance Heat
Arthritis 364 100.00 Very High Very High Very High
Inflammation 146 98.08 Very High Very High Very High
cytokine 95 97.04 Very High Very High Very High
rheumatoid arthritis 172 95.00 High High
metalloproteinase 21 5.00 Very Low Very Low Very Low
chemokine 12 5.00 Very Low Very Low Very Low
cINOD 11 5.00 Very Low Very Low Very Low
Inflammatory response 7 5.00 Very Low Very Low Very Low
antagonist 6 5.00 Very Low Very Low Very Low
methotrexate 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 388 100.00 Very High Very High Very High
INFLAMMATION 153 98.08 Very High Very High Very High
Rheumatoid Arthritis 172 95.00 High High
Death 15 90.72 High High
Disease 62 89.84 High High
Synovitis 10 81.20 Quite High
Pressure And Volume Under Development 29 56.48 Quite High
Autoimmune Disease 10 27.76 Quite Low
Apoptosis 39 5.00 Very Low Very Low Very Low
Severe Combined Immunodeficiency 24 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Likewise, collagen type II pulsed antigen presenting cells engineered to secret IL-4 down-regulated CIA [95].
Regulation (regulated) of CIA associated with arthritis
1) Confidence 0.03 Published 2008 Journal Mod Rheumatol Section Body Doc Link PMC2275302 Disease Relevance 1.19 Pain Relevance 0.58
In a follow-up experiment, we analyzed the possible therapeutic effects of these compounds in a mouse model of CIA.
Spec (possible) Regulation (effects) of CIA associated with arthritis
2) Confidence 0.03 Published 2007 Journal BMC Complement Altern Med Section Body Doc Link PMC1899520 Disease Relevance 0.82 Pain Relevance 0.28
Either intramuscular administration via electrotransfer or intra-dermal injection of plasmid encoding IL-10 had beneficial effects on CIA [31, 35].
Regulation (effects) of CIA associated with arthritis
3) Confidence 0.02 Published 2008 Journal Mod Rheumatol Section Body Doc Link PMC2275302 Disease Relevance 1.20 Pain Relevance 0.62
Kim et al. observed similar effects on CIA upon local and systemic administration of adenoviral vectors encoding IL-4 [88].
Regulation (effects) of CIA associated with arthritis
4) Confidence 0.02 Published 2008 Journal Mod Rheumatol Section Body Doc Link PMC2275302 Disease Relevance 1.16 Pain Relevance 0.53

General Comments

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