INT209607

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Context Info
Confidence 0.34
First Reported 2007
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 2.50
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
central nervous system 1
IGH@ (Homo sapiens)
Pain Link Frequency Relevance Heat
Central nervous system 13 98.60 Very High Very High Very High
Spinal cord 2 93.72 High High
peripheral neuropathy 12 87.36 High High
imagery 2 82.92 Quite High
dexamethasone 46 35.48 Quite Low
Pain 2 27.44 Quite Low
cva 10 5.00 Very Low Very Low Very Low
aspirin 5 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
vincristine 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Retinoblastoma 1 99.68 Very High Very High Very High
Lymphatic System Cancer 75 99.52 Very High Very High Very High
Chromosome Aberrations 5 99.20 Very High Very High Very High
Glycogen Storage Disease Type Vi 1 98.24 Very High Very High Very High
Hodgkin's Disease 4 96.16 Very High Very High Very High
Thrombocytopenia 13 92.72 High High
Disease 9 92.04 High High
Neutropenia 6 90.72 High High
Peripheral Neuropathy 12 87.36 High High
Infection 4 84.80 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Extranodal marginal zone lymphoma of the dura mater with IgH/MALT1 translocation and review of literature

Primary central nervous system lymphoma (PCNSL) is an extranodal non-Hodgkin lymphoma involving brain, intraocular structures and spinal cord, without evidence of systemic disease.

Localization (translocation) of IgH in central nervous system associated with lymphatic system cancer, hodgkin's disease, central nervous system, disease and spinal cord
1) Confidence 0.34 Published 2008 Journal J Hematop Section Title Doc Link PMC2713483 Disease Relevance 0.55 Pain Relevance 0.14
Responses were not conditioned by cytogenetic abnormalities, such as retinoblastoma gene deletion, IgH translocations and t(11; 14), t(4; 14), t(14; 16).
Localization (translocations) of IgH associated with chromosome aberrations and retinoblastoma
2) Confidence 0.26 Published 2007 Journal Clin Exp Med Section Body Doc Link PMC2779346 Disease Relevance 1.30 Pain Relevance 0.08
Gene locus translocations of myc, IgH, and bcl-2 were confirmed by FISH analysis in the second case.
Localization (translocations) of IgH
3) Confidence 0.05 Published 2007 Journal Mol Cancer Section Body Doc Link PMC1904237 Disease Relevance 0.64 Pain Relevance 0

General Comments

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