INT209708

Context Info Confidence 0.00 First Reported 2007 Last Reported 2007 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 0 Pain Relevance 0

cytoplasm (GABBR1, GTPBP4) Golgi apparatus (GTPBP4) GTPase activity (GTPBP4) ribosome biogenesis (GTPBP4) signal transducer activity (GABBR1) extracellular region (GABBR1)

GABBR1 (Homo sapiens) GTPBP4 (Homo sapiens)

Pain Link Frequency Relevance Heat opioid receptor 25 5.00 agonist 17 5.00 Opioid 15 5.00 Dopamine 9 5.00 antagonist 6 5.00 Cholecystokinin 5 5.00 Enkephalin 3 5.00 dopamine receptor 2 5.00 Glutamate 2 5.00 Potency 2 5.00

Disease Link Frequency Relevance Heat Urological Neuroanatomy 7 5.00 Targeted Disruption 2 5.00 Tics 1 5.00 Bordatella Infection 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The most unambiguous example of trans-activation has been described for the GABAB1-GABAB2 heterodimer, where the ligand-bound subunit (GABAB1) does not appear to couple to the G-protein, but the other subunit (GABAB2) within the hetero-dimer can bind the G-protein, but not the ligand [50].

GABAB1 Binding (couple) of G-protein

1) Confidence 0.00 Published 2007 Journal BMC Bioinformatics Section Body Doc Link PMC1904246 Disease Relevance 0 Pain Relevance 0

General Comments

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