INT209853

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Context Info
Confidence 0.61
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 6
Disease Relevance 3.41
Pain Relevance 1.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (TNF, CD36) transport (CD36) small molecule metabolic process (CD36)
Golgi apparatus (CD36) intracellular (TNF) extracellular matrix organization (TNF)
Anatomy Link Frequency
monocytes 4
TNF (Homo sapiens)
CD36 (Homo sapiens)
Pain Link Frequency Relevance Heat
Adalimumab 438 100.00 Very High Very High Very High
Inflammation 114 98.72 Very High Very High Very High
rheumatoid arthritis 66 97.48 Very High Very High Very High
cINOD 6 93.48 High High
aspirin 18 92.48 High High
dexamethasone 12 79.64 Quite High
cytokine 42 45.28 Quite Low
antagonist 6 21.84 Low Low
Inflammatory response 12 18.92 Low Low
methotrexate 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Necrosis 24 100.00 Very High Very High Very High
Cancer 24 100.00 Very High Very High Very High
INFLAMMATION 132 98.72 Very High Very High Very High
Disease 48 98.20 Very High Very High Very High
Rheumatoid Arthritis 66 97.48 Very High Very High Very High
Increased Venous Pressure Under Development 72 87.56 High High
Repression 12 85.60 High High
Atherosclerosis 42 82.52 Quite High
Congenital Anomalies 6 64.64 Quite High
Adhesions 24 55.68 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These factors have prompted us to test the hypothesis that CD36 expression in human monocytes is regulated by TNF?
TNF Regulation (regulated) of Gene_expression (expression) of CD36 in monocytes
1) Confidence 0.61 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906797 Disease Relevance 0.67 Pain Relevance 0.38
The role of ROS production in the regulation of CD36 expression induced by TNF?
TNF Regulation (regulation) of Gene_expression (expression) of CD36
2) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906797 Disease Relevance 0.09 Pain Relevance 0
Our work demonstrates differential regulation of CD36 expression by TNF?
TNF Regulation (regulation) of Gene_expression (expression) of CD36
3) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906797 Disease Relevance 0.99 Pain Relevance 0.36
Regulation of CD36 membrane expression by TNF?
TNF Regulation (Regulation) of Gene_expression (expression) of CD36
4) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906797 Disease Relevance 0 Pain Relevance 0.08
Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes

In chronic inflammatory diseases, such as rheumatoid arthritis, inflammation acts as an independent cardiovascular risk factor and the use of anti-inflammatory drugs, such as anti-tumor necrosis factor alpha (anti-TNF?)

Tumor necrosis factor Regulation (regulate) of Gene_expression (expression) of CD36 in monocytes associated with necrosis, inflammation, cancer, cinod, rheumatoid arthritis, adalimumab and disease
5) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Title Doc Link PMC1906797 Disease Relevance 0.95 Pain Relevance 0.39
Our work shows differential regulation of CD36 expression by TNF?
TNF Regulation (regulation) of Gene_expression (expression) of CD36
6) Confidence 0.27 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906797 Disease Relevance 0.71 Pain Relevance 0.37

General Comments

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