INT209902

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Context Info
Confidence 0.47
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 2.14
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TRAF1) protein complex assembly (TRAF1) cytoplasm (TRAF1)
TRAF1 (Homo sapiens)
Pain Link Frequency Relevance Heat
rheumatoid arthritis 136 98.84 Very High Very High Very High
Inflammation 35 84.72 Quite High
Arthritis 156 56.80 Quite High
cytokine 12 7.72 Low Low
Osteoarthritis 10 5.00 Very Low Very Low Very Low
Multiple sclerosis 4 5.00 Very Low Very Low Very Low
Crohn's disease 4 5.00 Very Low Very Low Very Low
spinal inflammation 2 5.00 Very Low Very Low Very Low
cINOD 1 5.00 Very Low Very Low Very Low
psoriasis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 136 98.84 Very High Very High Very High
Apoptosis 8 98.56 Very High Very High Very High
INFLAMMATION 32 84.72 Quite High
Wegener's Granulomatosis 2 57.36 Quite High
Juvenile Chronic Polyarthritis 144 56.80 Quite High
Arthritis 13 51.88 Quite High
Disease Susceptibility 4 50.00 Quite Low
Seronegative Spondarthritis 1 41.72 Quite Low
Autoimmune Disease 22 8.36 Low Low
Disease 30 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
TRAF1/C5: Three SNPs located in the TRAF1/C5 region were identified for investigation, one of which (rs10818488) showed the strongest evidence for association with Dutch RA cases.15 The other two SNPs, rs3761847 and rs2900180, showed the strongest evidence for association in North American and Swedish RA cases.16
Positive_regulation (/) of TRAF1 associated with rheumatoid arthritis
1) Confidence 0.47 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2935325 Disease Relevance 0.76 Pain Relevance 0.38
TRAF1/C5: Three SNPs located in the TRAF1/C5 region were identified for investigation, one of which (rs10818488) showed the strongest evidence for association with Dutch RA cases.15 The other two SNPs, rs3761847 and rs2900180, showed the strongest evidence for association in North American and Swedish RA cases.16
Positive_regulation (identified) of TRAF1 associated with rheumatoid arthritis
2) Confidence 0.47 Published 2010 Journal Annals of the Rheumatic Diseases Section Body Doc Link PMC2935325 Disease Relevance 0.83 Pain Relevance 0.41
B and TRAF1 induction [45].
Positive_regulation (induction) of TRAF1
3) Confidence 0.21 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906801 Disease Relevance 0.55 Pain Relevance 0.20

General Comments

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