INT209962

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Context Info
Confidence 0.11
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 2.93
Pain Relevance 1.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (RDBP) mitochondrion (RDBP) nucleolus (RDBP)
RNA binding (RDBP) nucleus (RDBP) biological_process (RDBP)
Anatomy Link Frequency
T-cell 3
RDBP (Homo sapiens)
Pain Link Frequency Relevance Heat
spinal inflammation 59 95.72 Very High Very High Very High
rheumatoid arthritis 11 89.52 High High
abatacept 74 87.20 High High
methotrexate 4 74.00 Quite High
Arthritis 6 70.80 Quite High
psoriasis 1 60.80 Quite High
COX2 2 59.96 Quite High
cINOD 5 58.96 Quite High
Pain 14 55.32 Quite High
spondylitis 16 48.80 Quite Low
Disease Link Frequency Relevance Heat
Cancer 102 99.56 Very High Very High Very High
Skin Cancer 2 99.10 Very High Very High Very High
Low Back Pain 82 95.72 Very High Very High Very High
Ovarian Cancer 1 95.64 Very High Very High Very High
Rheumatoid Arthritis 12 89.52 High High
Colon Cancer 3 87.28 High High
Small Cell Lung Cancer 1 84.40 Quite High
Lung Cancer 2 83.24 Quite High
Genetic Predisposition To Disease 1 82.80 Quite High
Disease 33 82.48 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
3. to investigate whether formation of particular RBC antibodies is associated with maternal Major Histocompatibility Complex (MHC) class II alleles
Major Histocompatibility Complex Binding (associated) of
1) Confidence 0.11 Published 2010 Journal BMC Pregnancy Childbirth Section Body Doc Link PMC3003623 Disease Relevance 0.18 Pain Relevance 0
The T-cell receptor theory is based on knowledge that this receptor recognizes only peptides that are in association with class I or class II MHC (Major Histocompatibility Complex) molecules.
Major Histocompatibility Complex Binding (association) of in T-cell
2) Confidence 0.10 Published 2007 Journal Biologics : Targets & Therapy Section Body Doc Link PMC2721344 Disease Relevance 0.95 Pain Relevance 0.57
The first signal is mediated through the T-cell receptor via an interaction with major histocompatibility complex-presented peptide antigen [6].
major histocompatibility complex-presented Binding (interaction) of in T-cell
3) Confidence 0.05 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1906816 Disease Relevance 0.29 Pain Relevance 0.70
SART3 (squamous cell carcinoma antigen recognized by T cells 3), is an RNA-binding nuclear protein that is a tumor-rejection antigen.
nuclear protein Binding (binding) of in T cells associated with cancer and skin cancer
4) Confidence 0.02 Published 2007 Journal Cancer Informatics Section Body Doc Link PMC2675843 Disease Relevance 1.51 Pain Relevance 0

General Comments

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