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Context Info
Confidence 0.08
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (LDLR, LRP1) endosome (LRP1) transport (LDLR)
aging (LRP1) small molecule metabolic process (LDLR) cytoplasm (LRP1)
Anatomy Link Frequency
macrophages 1
LDLR (Homo sapiens)
LRP1 (Homo sapiens)
Pain Link Frequency Relevance Heat
lidocaine 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 17 50.00 Quite Low
Atherosclerosis 3 5.00 Very Low Very Low Very Low
Atherosclerotic Plaque 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The different rates of uptake of CRLPs oxCRLPs and pCRLPs by macrophages demonstrated here, therefore, could be explained by effects on interaction with the LDLr and the LRP caused by differences both in the conformation of apoE and in the number of apoE molecules able to bind to the receptors, even though the total amount of apoE associated with the particles is not changed.
LDLr Binding (interaction) of LRP in macrophages
1) Confidence 0.08 Published 2007 Journal Biochim Biophys Acta Section Body Doc Link PMC1906864 Disease Relevance 0 Pain Relevance 0

General Comments

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