INT210015

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Context Info
Confidence 0.47
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.88
Pain Relevance 1.00

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Adcyap1, Crh) extracellular region (Adcyap1, Crh) cytosol (Adcyap1)
signal transduction (Adcyap1) response to stress (Crh) cytoplasm (Crh)
Anatomy Link Frequency
neurons 1
Adcyap1 (Rattus norvegicus)
Crh (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Neuropeptide 8 100.00 Very High Very High Very High
Neurotransmitter 4 100.00 Very High Very High Very High
medulla 4 93.32 High High
Dorsal horn 2 92.48 High High
primary afferent fibers 2 90.88 High High
amygdala 164 87.04 High High
Glutamate 2 86.12 High High
antagonist 4 43.20 Quite Low
Autonomic response 2 42.60 Quite Low
parabrachial 2 35.72 Quite Low
Disease Link Frequency Relevance Heat
Anxiety Disorder 78 99.14 Very High Very High Very High
Stress 22 90.40 High High
Shock 108 78.80 Quite High
Urological Neuroanatomy 2 35.16 Quite Low
Pain 2 5.00 Very Low Very Low Very Low
INFLAMMATION 2 5.00 Very Low Very Low Very Low
Necrosis 2 5.00 Very Low Very Low Very Low
Hemorrhage 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interactions between PACAP and other neuropeptides/neurotransmitters, such as CRH, are quite likely to occur.
PACAP Binding (Interactions) of CRH associated with neurotransmitter and neuropeptide
1) Confidence 0.47 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1906870 Disease Relevance 0.47 Pain Relevance 0.50
Based on earlier reports, we hypothesize that the effects of PACAP on fear-related behaviors may be mediated through interaction between PACAP and CRH neurons at hypothalamic, as well as extrahypothalamic, sites

(Kozicz et al. [20];

PACAP Binding (interaction) of CRH in neurons associated with anxiety disorder
2) Confidence 0.35 Published 2007 Journal Neural Plasticity Section Body Doc Link PMC1906870 Disease Relevance 0.40 Pain Relevance 0.50

General Comments

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