INT210022

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Context Info
Confidence 0.01
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.02
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Thim (Mus musculus)
Thim - E528D (1) Thim - T175A (1)
Pain Link Frequency Relevance Heat
adenocard 3 94.64 High High
Bile 84 5.00 Very Low Very Low Very Low
Inflammation 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Syndrome 96 95.72 Very High Very High Very High
Gallstones 249 95.36 Very High Very High Very High
Disease 30 84.80 Quite High
Intrahepatic Cholestasis 30 57.92 Quite High
Recurrence 36 19.80 Low Low
Liver Disease 18 5.00 Very Low Very Low Very Low
Pancreatitis 12 5.00 Very Low Very Low Very Low
Biliary Liver Cirrhosis 12 5.00 Very Low Very Low Very Low
Primary Sclerosing Cholangitis 12 5.00 Very Low Very Low Very Low
Cholangitis 12 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The Phe165Ile mutation was localized in the same part of this intracellular loop and may therefore give rise to a similar defect.
Localization (localized) of mutation (F165I)
1) Confidence 0.01 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1910597 Disease Relevance 0.31 Pain Relevance 0.05
The Thr175Ala mutation was localized in the 1st intracellular loop and resulted in a substitution in a conserved cluster of four amino-acids at position 169–172, required for the adenosine triphosphatase activity of the molecule.
Localization (localized) of mutation (T175A) associated with adenocard
2) Confidence 0.01 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1910597 Disease Relevance 0.36 Pain Relevance 0.05
The Glu528Asp mutation was localized close to the NBD1.
Localization (localized) of mutation (E528D)
3) Confidence 0.01 Published 2007 Journal Orphanet J Rare Dis Section Body Doc Link PMC1910597 Disease Relevance 0.35 Pain Relevance 0.04

General Comments

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