INT210075

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Context Info
Confidence 0.67
First Reported 2006
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.98
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (MIP) transmembrane transport (MIP)
Anatomy Link Frequency
lung 1
MIP (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 47 98.64 Very High Very High Very High
rheumatoid arthritis 52 94.72 High High
Inflammatory response 5 88.20 High High
Inflammation 40 74.80 Quite High
diclofenac 1 58.56 Quite High
chemokine 5 49.76 Quite Low
COX-2 inhibitor 2 46.00 Quite Low
cINOD 1 14.80 Low Low
Arthritis 5 10.24 Low Low
metalloproteinase 25 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Adhesions 7 99.32 Very High Very High Very High
Rheumatoid Arthritis 52 94.72 High High
INFLAMMATION 46 87.84 High High
Dermatitis 9 86.20 High High
Skin Diseases 2 72.08 Quite High
Erythema 3 69.36 Quite High
Toxicity 5 54.72 Quite High
Apoptosis 28 40.40 Quite Low
Pressure And Volume Under Development 6 30.64 Quite Low
Disease 19 29.60 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
2 integrin/vascular cell adhesion molecule (VCAM)-1 resulted in an upregulation of MIP-1?
Positive_regulation (upregulation) of MIP associated with adhesions
1) Confidence 0.67 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC2246247 Disease Relevance 0.34 Pain Relevance 0.27
Increased levels of IL-8, MIP-1?
Positive_regulation (Increased) of MIP
2) Confidence 0.45 Published 2007 Journal Environ Health Perspect Section Body Doc Link PMC1913569 Disease Relevance 0.64 Pain Relevance 0.29
MIP decreases as lung volume increases, while maximum expiratory pressure changes in the opposite direction (Agostoni and Hyatt 1986), therefore at high volumes a greater fraction of maximum effort is required to generate the same pressure.
Positive_regulation (increases) of MIP in lung
3) Confidence 0.24 Published 2006 Journal International Journal of Chronic Obstructive Pulmonary Disease Section Body Doc Link PMC2707802 Disease Relevance 0 Pain Relevance 0

General Comments

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