INT2101

Context Info Confidence 0.31 First Reported 1978 Last Reported 2005 Negated 0 Speculated 0 Reported most in Body Documents 2 Total Number 2 Disease Relevance 0.29 Pain Relevance 0.40

isomerase activity (Pdia4) endoplasmic reticulum (Pdia4)

Anatomy Link Frequency blood 1 Pdia4 (Mus musculus)

Pain Link Frequency Relevance Heat antagonist 10 100.00 Angina 4 95.44 methadone 3 50.00 addiction 1 5.00 MU agonist 1 5.00

Disease Link Frequency Relevance Heat Cv General 3 Under Development 4 95.44 Central Sleep Apnea 4 69.36 Opiate Addiction 1 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

The effects of the association of calcium antagonists (CAI) with a nitroderivate and a betablocker were studied by means of exercise tests in 8 patients with stable effort angina pectoris.

CAI Binding (association) of associated with angina and antagonist

1) Confidence 0.31 Published 1978 Journal G Ital Cardiol Section Abstract Doc Link 348546 Disease Relevance 0.22 Pain Relevance 0.40

Methadone blood concentration was the only significant variable (t = 2.33, p = 0.025) associated with CAI and explains 12% of the variance.

CAI Binding (associated) of in blood

2) Confidence 0.16 Published 2005 Journal Chest Section Body Doc Link 16162728 Disease Relevance 0.07 Pain Relevance 0

General Comments

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