INT210197

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Context Info
Confidence 0.63
First Reported 2007
Last Reported 2007
Negated 2
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.19
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (TXN) transport (TXN) mitochondrion (TXN)
small molecule metabolic process (TXN) cell-cell signaling (TXN) cytoplasm (TXN)
Anatomy Link Frequency
HeLa 2
TXN (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 9 50.00 Quite Low
Inflammation 24 5.00 Very Low Very Low Very Low
member 8 6 5.00 Very Low Very Low Very Low
agonist 3 5.00 Very Low Very Low Very Low
rheumatoid arthritis 3 5.00 Very Low Very Low Very Low
Inflammatory response 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Epstein-barr Virus 6 85.84 High High
Leukemia 6 54.96 Quite High
Lymphatic System Cancer 21 52.56 Quite High
INFLAMMATION 27 5.00 Very Low Very Low Very Low
Apoptosis 12 5.00 Very Low Very Low Very Low
Viral Infection 9 5.00 Very Low Very Low Very Low
Stress 9 5.00 Very Low Very Low Very Low
Adhesions 6 5.00 Very Low Very Low Very Low
Necrosis 6 5.00 Very Low Very Low Very Low
Cancer 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, expression of CD95 (Figure 4D), TNFR1 or NGFR (data not shown) did not promote Trx1 interactions with the cell surface, further strengthening the notion that Trx1 reactivity is a specific property of CD30.
Neg (not) Positive_regulation (promote) of Trx1 Neg (not) Binding (interactions) of
1) Confidence 0.63 Published 2007 Journal EMBO J Section Body Doc Link PMC1914094 Disease Relevance 0.11 Pain Relevance 0
Kinetic trapping on the surface of lymphoid cell lines identifies a prominent Trx1 interaction partner
Positive_regulation (prominent) of Trx1 Binding (partner) of
2) Confidence 0.46 Published 2007 Journal EMBO J Section Body Doc Link PMC1914094 Disease Relevance 0.09 Pain Relevance 0
While mock-transfected HeLa cells did not capture Trx1(CSAAA) on their surface (Figure 4C, lower row), expression of CD30 led to a strong Trx1 surface association and colocalization of both proteins (Figure 4C, upper row).
Neg (not) Positive_regulation (led) of Trx1 Binding (association) of in HeLa
3) Confidence 0.37 Published 2007 Journal EMBO J Section Body Doc Link PMC1914094 Disease Relevance 0 Pain Relevance 0

General Comments

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