INT210225

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Context Info
Confidence 0.15
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.44
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

phosphatase activity (Ptpn2) extracellular space (Ifng) extracellular region (Ifng)
endoplasmic reticulum (Ptpn2) nucleus (Ptpn2) cytoplasm (Ptpn2)
Anatomy Link Frequency
substantia nigra 2
Ptpn2 (Mus musculus)
Ifng (Mus musculus)
Pain Link Frequency Relevance Heat
Substantia nigra 1 97.64 Very High Very High Very High
Inflammatory mediators 1 91.16 High High
cytokine 15 77.76 Quite High
Inflammation 27 72.28 Quite High
cerebral cortex 1 53.88 Quite High
Multiple sclerosis 2 34.84 Quite Low
imagery 1 32.48 Quite Low
ischemia 17 5.00 Very Low Very Low Very Low
sSRI 2 5.00 Very Low Very Low Very Low
Inflammatory response 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Parkinson's Disease 2 100.00 Very High Very High Very High
Disease 6 99.96 Very High Very High Very High
INFLAMMATION 30 90.76 High High
Toxicity 3 90.40 High High
Autism 65 89.20 High High
Targeted Disruption 1 88.64 High High
Congenital Anomalies 8 83.04 Quite High
Cognitive Disorder 3 81.80 Quite High
Cancer 1 77.52 Quite High
Dementia 1 61.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
For example, the common neurotoxin used in models of Parkinson's Disease, MPTP is believed to mediate its activity through activation of IFN-gamma production, leading to direct killing of dopaminergic neurons in the substantia nigra.
MPTP Positive_regulation (activation) of Gene_expression (production) of IFN-gamma in substantia nigra associated with parkinson's disease, substantia nigra and disease
1) Confidence 0.15 Published 2007 Journal J Transl Med Section Body Doc Link PMC1914111 Disease Relevance 1.44 Pain Relevance 0.42

General Comments

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