INT210387

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Context Info
Confidence 0.13
First Reported 2007
Last Reported 2009
Negated 1
Speculated 0
Reported most in Body
Documents 3
Total Number 4
Disease Relevance 2.31
Pain Relevance 0.20

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (FUT1) Golgi apparatus (FUT1) carbohydrate metabolic process (FUT1)
Anatomy Link Frequency
HSC 2
kidney 2
FUT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 22 99.98 Very High Very High Very High
fibrosis 29 88.44 High High
chemokine 10 79.84 Quite High
ischemia 9 34.32 Quite Low
Inflammation 54 15.84 Low Low
Inflammatory response 11 5.00 Very Low Very Low Very Low
Bile 6 5.00 Very Low Very Low Very Low
alcohol 5 5.00 Very Low Very Low Very Low
Versed 4 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cirrhosis 155 100.00 Very High Very High Very High
Fibrosis 45 99.52 Very High Very High Very High
Apoptosis 70 88.00 High High
Injury 97 85.92 High High
Disease 25 73.92 Quite High
Necrosis 14 51.48 Quite High
Wound Healing 12 50.00 Quite Low
Liver Disease 44 47.60 Quite Low
Sepsis 2 40.80 Quite Low
Shock 3 40.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
receptor (pPBHSA) may be quite relevant, since PDGF-BB is the major cytokine involved in the proliferation of HSC during the fibrotic process, and the PDGF-?
Regulation (involved) of HSC Binding (proliferation) of associated with fibrosis, cirrhosis and cytokine
1) Confidence 0.13 Published 2007 Journal Pharm Res Section Body Doc Link PMC1915609 Disease Relevance 1.52 Pain Relevance 0.13
In sharp contrast to studies in other injured organs, our results indicate that migration of HSC to the ischemic damaged kidney is not solely dependent on the SDF-1/CXCR4 signalling axis.



Neg (not) Regulation (dependent) of HSC Binding (migration) of in kidney
2) Confidence 0.09 Published 2009 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2698094 Disease Relevance 0.12 Pain Relevance 0.04
The mechanisms that regulate the trafficking of HSC to the ischemic damaged kidney, however, remain unclear.
Regulation (regulate) of HSC Binding (trafficking) of in HSC
3) Confidence 0.09 Published 2009 Journal Nephrology Dialysis Transplantation Section Body Doc Link PMC2698094 Disease Relevance 0.32 Pain Relevance 0.04
Activation of HSCs as well as proliferation of HSC/MFs have been suggested to rely on the activation of NF-?
Regulation (rely) of HSC Binding (proliferation) of associated with cirrhosis
4) Confidence 0.05 Published 2008 Journal Fibrogenesis Tissue Repair Section Body Doc Link PMC2584013 Disease Relevance 0.35 Pain Relevance 0

General Comments

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