INT210525

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Context Info
Confidence 0.40
First Reported 2005
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.93
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ide) mitochondrion (Ide) extracellular space (Ide)
ATPase activity (Ide) nucleus (Ide)
Ide (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 8 99.90 Very High Very High Very High
Inflammation 6 99.28 Very High Very High Very High
agonist 12 91.76 High High
substance P 4 50.96 Quite High
Enkephalin 1 49.68 Quite Low
withdrawal 1 44.32 Quite Low
Kinase C 13 5.00 Very Low Very Low Very Low
Central nervous system 8 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
cINOD 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 10 99.90 Very High Very High Very High
INFLAMMATION 7 99.28 Very High Very High Very High
Alzheimer's Dementia 43 97.68 Very High Very High Very High
Disease 88 96.64 Very High Very High Very High
Diabetes Mellitus 3 96.36 Very High Very High Very High
Insulin Resistance 5 90.92 High High
Body Weight 11 76.80 Quite High
Amyloid Plaque 10 75.08 Quite High
Death 5 62.96 Quite High
Neurodegenerative Disease 16 57.04 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IDE cleaves a broad range of peptides and has been proposed to be an amyloid scavenger recognizing structural ?
Transcription (cleaves) of IDE associated with alzheimer's dementia
1) Confidence 0.40 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1920558 Disease Relevance 1.04 Pain Relevance 0.03
Glucose tolerance and insulin sensitivity
Transcription (sensitivity) of insulin associated with tolerance and impaired glucose tolerance
2) Confidence 0.40 Published 2005 Journal Purinergic Signal Section Body Doc Link PMC2096536 Disease Relevance 0.26 Pain Relevance 0.05
Most of the neuroprotective effects of TZDs are ascribed to either improved insulin sensitivity or to their anti-inflammatory action through PPAR?
Transcription (sensitivity) of insulin associated with inflammation
3) Confidence 0.04 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.62 Pain Relevance 0.13

General Comments

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