INT210533

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Context Info
Confidence 0.25
First Reported 2007
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 1.93
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Ide) mitochondrion (Ide) extracellular space (Ide)
ATPase activity (Ide) nucleus (Ide)
Ide (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 50 81.56 Quite High
imagery 5 62.20 Quite High
substance P 8 57.92 Quite High
Enkephalin 2 56.64 Quite High
cINOD 23 5.00 Very Low Very Low Very Low
Hippocampus 9 5.00 Very Low Very Low Very Low
positron emission tomography 5 5.00 Very Low Very Low Very Low
cytokine 5 5.00 Very Low Very Low Very Low
Central nervous system 4 5.00 Very Low Very Low Very Low
long-term potentiation 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Alzheimer's Dementia 115 100.00 Very High Very High Very High
Disease 181 97.76 Very High Very High Very High
INFLAMMATION 53 81.56 Quite High
Amyloid Plaque 9 75.08 Quite High
Death 4 69.92 Quite High
Aging 7 57.80 Quite High
Vascular Dementia 1 53.84 Quite High
Creutzfeldt Jakob Disease 2 52.40 Quite High
Syndrome 4 49.72 Quite Low
Neurodegenerative Disease 22 49.32 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
IDE cleaves a broad range of peptides and has been proposed to be an amyloid scavenger recognizing structural ?
Negative_regulation (scavenger) of IDE Binding (recognizing) of associated with alzheimer's dementia
1) Confidence 0.25 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1920558 Disease Relevance 1.07 Pain Relevance 0.09
IDE has been proposed to be an amyloid scavenger recognizing structural ?
Negative_regulation (scavenger) of IDE Binding (recognizing) of associated with alzheimer's dementia
2) Confidence 0.25 Published 2007 Journal PLoS ONE Section Body Doc Link PMC1920558 Disease Relevance 0.28 Pain Relevance 0
This is an important finding because it represents an uncoupling of both insulin and neurotrophic factor signaling to the critical neuroprotective PI3-K/Akt pathway [161].DHA modestly suppressed A?
Negative_regulation (represents) of insulin Binding (uncoupling) of
3) Confidence 0.02 Published 2010 Journal Mol Neurobiol Section Body Doc Link PMC2876259 Disease Relevance 0.58 Pain Relevance 0.07

General Comments

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