INT210585

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Context Info
Confidence 0.24
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.39
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pthlh) Golgi apparatus (Pthlh) nucleus (Pthlh)
intracellular (Pthlh) cytoplasm (Pthlh)
Pthlh (Mus musculus)
Pain Link Frequency Relevance Heat
corticosteroid 2 49.68 Quite Low
cytokine 8 18.80 Low Low
chemokine 6 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
Inflammation 4 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 29 99.68 Very High Very High Very High
Malignant Neoplastic Disease 5 99.64 Very High Very High Very High
Hypercalcemia 59 99.36 Very High Very High Very High
Solid Tumor 3 93.52 High High
Plasma Cell Leukemia 3 69.44 Quite High
Renal Insufficiency 1 67.96 Quite High
Multiple Myeloma 9 50.00 Quite Low
Bone Cancer 19 36.56 Quite Low
Disease 5 23.76 Low Low
Osteoporosis 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
First, in contrast to myeloma patients with hypercalcemia, in which PTHrP is implicated only sporadically, humoral hypercalcemia of malignancy is almost always due to excessive secretion of PTHrP by the tumor, resulting in elevated circulating levels.
Positive_regulation (due) of Localization (secretion) of PTHrP associated with malignant neoplastic disease, cancer and hypercalcemia
1) Confidence 0.24 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924519 Disease Relevance 1.39 Pain Relevance 0

General Comments

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