INT210587

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Context Info
Confidence 0.18
First Reported 2004
Last Reported 2007
Negated 1
Speculated 1
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.17
Pain Relevance 0.03

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (Pthlh) Golgi apparatus (Pthlh) nucleus (Pthlh)
intracellular (Pthlh) cytoplasm (Pthlh)
Anatomy Link Frequency
growth plate 1
Pthlh (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 6 54.16 Quite High
cytokine 8 48.88 Quite Low
Spinal cord 1 28.04 Quite Low
Pain 3 26.20 Quite Low
chemokine 6 5.00 Very Low Very Low Very Low
antagonist 5 5.00 Very Low Very Low Very Low
imagery 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
depression 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypercalcemia 59 88.24 High High
Plasma Cell Leukemia 3 84.40 Quite High
Cancer 42 78.12 Quite High
Disease 6 74.76 Quite High
Bone Cancer 25 68.96 Quite High
Renal Insufficiency 1 66.24 Quite High
Osteoarthritis 3 58.44 Quite High
Necrosis 2 55.64 Quite High
INFLAMMATION 6 54.16 Quite High
Multiple Hereditary Exostoses 45 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Elevated serum PTHrP is not a consistent finding in myeloma patients, and it remains unclear why myeloma patients present with increased renal tubular calcium reabsorption.
PTHrP Neg (not) Spec (finding) Binding (finding) of
1) Confidence 0.18 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924519 Disease Relevance 1.11 Pain Relevance 0.03
Indian Hedgehog (IHh)/PTHrP signalling in the growth plate
PTHrP Binding (Indian) of in growth plate
2) Confidence 0.05 Published 2004 Journal Hered Cancer Clin Pract Section Body Doc Link PMC2840003 Disease Relevance 0.06 Pain Relevance 0

General Comments

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