INT210594

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Context Info
Confidence 0.15
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.77
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (TNFRSF11B, TNFRSF11A) extracellular region (TNFRSF11B) proteinaceous extracellular matrix (TNFRSF11B)
extracellular matrix organization (TNFRSF11B) cell-cell signaling (TNFRSF11A)
TNFRSF11B (Homo sapiens)
TNFRSF11A (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 6 77.04 Quite High
antagonist 4 5.00 Very Low Very Low Very Low
metalloproteinase 2 5.00 Very Low Very Low Very Low
chemokine 2 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 5 98.64 Very High Very High Very High
Metastasis 92 80.64 Quite High
Cancer 66 79.36 Quite High
Osteoporosis 45 68.44 Quite High
Breast Cancer 12 57.52 Quite High
Hypercalcemia 3 55.76 Quite High
Osteolysis 16 50.00 Quite Low
Disease Progression 1 42.72 Quite Low
Prostate Cancer 17 35.92 Quite Low
Lung Cancer 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OPG is a negative regulator of the RANK/RANKL pathway and prevents RANK-RANKL interaction by sequestering RANKL.
OPG Negative_regulation (prevents) of RANK Binding (interaction) of
1) Confidence 0.15 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924520 Disease Relevance 0.77 Pain Relevance 0.04

General Comments

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