INT210595

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Context Info
Confidence 0.10
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 4
Disease Relevance 5.13
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

intracellular (TNF, TNFSF11) extracellular space (TNF, TNFSF11) extracellular region (TNF, TNFSF11)
plasma membrane (TNF, TNFSF11) cell differentiation (TNFSF11) extracellular matrix organization (TNF)
Anatomy Link Frequency
stromal cells 1
osteoblast 1
TNF (Homo sapiens)
TNFSF11 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 24 90.60 High High
antagonist 16 5.00 Very Low Very Low Very Low
metalloproteinase 8 5.00 Very Low Very Low Very Low
chemokine 8 5.00 Very Low Very Low Very Low
Pain 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 264 100.00 Very High Very High Very High
Necrosis 8 100.00 Very High Very High Very High
Metastasis 368 99.60 Very High Very High Very High
Osteoporosis 180 97.44 Very High Very High Very High
Prostate Cancer 68 95.36 Very High Very High Very High
Osteolysis 64 85.20 High High
Disease Progression 4 78.64 Quite High
Apoptosis 20 34.40 Quite Low
Malignant Neoplastic Disease 8 32.68 Quite Low
Adhesions 4 23.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
RANKL is a member of the TNF ligand superfamily and is expressed on numerous cell types, including osteoblast/stromal cells [35].
TNF Binding (ligand) of RANKL in stromal cells associated with osteoporosis
1) Confidence 0.10 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924520 Disease Relevance 0.97 Pain Relevance 0
B ligand (RANKL), and tumor necrosis factor (TNF)-?
tumor necrosis factor Binding (ligand) of RANKL associated with necrosis and cancer
2) Confidence 0.09 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924520 Disease Relevance 1.59 Pain Relevance 0.05
B ligand (RANKL), and tumor necrosis factor (TNF)-?
TNF Binding (ligand) of RANKL associated with necrosis and cancer
3) Confidence 0.09 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924520 Disease Relevance 1.59 Pain Relevance 0.05
RANKL is a member of the TNF ligand superfamily and is expressed on numerous cell types, including osteoblast/stromal cells [35].
TNF Binding (ligand) of RANKL in osteoblast associated with osteoporosis
4) Confidence 0.03 Published 2007 Journal Arthritis Res Ther Section Body Doc Link PMC1924520 Disease Relevance 0.97 Pain Relevance 0

General Comments

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