INT210686

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Context Info
Confidence 0.12
First Reported 2007
Last Reported 2010
Negated 1
Speculated 0
Reported most in Abstract
Documents 2
Total Number 2
Disease Relevance 0.91
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular space (F3) aging (F3) cytoplasm (F3)
Anatomy Link Frequency
plasma 1
monocytes 1
F3 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
cytokine 3 97.60 Very High Very High Very High
Inflammation 6 87.12 High High
Inflammatory response 1 69.60 Quite High
Angina 2 5.00 Very Low Very Low Very Low
aspirin 1 5.00 Very Low Very Low Very Low
ischemia 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
cva 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Sepsis 34 90.04 High High
Shock 3 88.76 High High
INFLAMMATION 5 87.12 High High
Inflammatory Bowel Disease 1 80.64 Quite High
Diabetes Mellitus 21 78.68 Quite High
Systemic Inflammatory Response Syndrome 1 69.96 Quite High
Endotoxemia 1 40.40 Quite Low
Renal Failure 1 9.76 Low Low
Disseminated Intravascular Coagulation 9 7.60 Low Low
Cardiovascular Disease 7 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In addition to these effects, Vitamin D may also inhibit the cytokines effect on target cells. vitamin D has an antagonistic effect on TNF-alpha stimulation of monocytes in cultures by down-regulating the surface protein tissue factor (TF) and up-regulating trombomodulin (TM) expression in monocytic cells 18.
Regulation (regulating) of tissue factor in monocytes associated with cytokine
1) Confidence 0.12 Published 2007 Journal International Journal of Medical Sciences Section Body Doc Link PMC1925152 Disease Relevance 0.54 Pain Relevance 0.23
There were no effects of particles on plasma tissue factor, coagulation factors VII or IX, or D-dimer.


Neg (no) Regulation (effects) of tissue factor in plasma
2) Confidence 0.00 Published 2010 Journal Environ Health Perspect Section Abstract Doc Link PMC3002188 Disease Relevance 0.37 Pain Relevance 0.04

General Comments

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