INT210693
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
We and others have proposed that GABAergic mechanisms may explain allodynia in inflamed conditions such that NKCC1 activity increases leading to a large depolarization in C-fibers, causing spiking, in response to A? | |||||||||||||||
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The NKCC1 cotransporter responds to relative changes in ion concentrations (see Methods), and as [Na+]o and [Cl?] | |||||||||||||||
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o during stimulation (compared to [9],[13] whereas mc3 and mc5 associated with H3 and H5 (NBC only and NBC+NKCC1, respectively) predict an increase in [Cl?] | |||||||||||||||
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-cotransporter (NKCC1) which sets up a Cl? | |||||||||||||||
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cotransporter (NKCC), which mediates Cl? | |||||||||||||||
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General Comments
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