INT210764

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Context Info
Confidence 0.66
First Reported 2007
Last Reported 2009
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 0.65
Pain Relevance 0.90

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleolus (Klf15) nucleus (Klf15) intracellular (Klf15)
DNA binding (Klf15)
Klf15 (Mus musculus)
Pain Link Frequency Relevance Heat
dexamethasone 282 98.04 Very High Very High Very High
Morphine 172 97.64 Very High Very High Very High
metalloproteinase 6 96.70 Very High Very High Very High
antagonist 8 80.48 Quite High
Eae 7 48.40 Quite Low
Opioid 28 43.24 Quite Low
tolerance 8 42.36 Quite Low
withdrawal 9 34.88 Quite Low
adenocard 2 33.52 Quite Low
Physical dependence 10 29.60 Quite Low
Disease Link Frequency Relevance Heat
Sprains And Strains 246 93.40 High High
Body Weight 5 85.20 High High
Weight Gain 1 83.92 Quite High
Opiate Addiction 8 34.88 Quite Low
Left Ventricular Hypertrophy 7 29.64 Quite Low
Drug Dependence 12 29.60 Quite Low
Fibrosis 2 18.92 Low Low
Myocardial Infarction 2 9.04 Low Low
Cv Unclassified Under Development 1 8.32 Low Low
Apoptosis 17 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In contrast, the expression pattern for Klf15 exhibits a higher fold-change difference in the microarrays compared to the control.
Gene_expression (expression) of Klf15
1) Confidence 0.66 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1929075 Disease Relevance 0 Pain Relevance 0.21
Probes for Indian hedgehog (Ihh), Tissue inhibitor of matrix metalloproteinase 4 (Timp4), Cyclin-dependent kinase inhibitor 1C (Cdkn1c, p57), Integrin beta like 1 protein (Itgbl1), GC receptor (Nr3c1), Integrin beta 1 (Itgb1) and Kruppel-like factor 15 (Klf15) were assayed using the TaqMan® gene expression assays in accordance with the manufacturers directions.
Gene_expression (expression) of Klf15 associated with metalloproteinase
2) Confidence 0.57 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1929075 Disease Relevance 0 Pain Relevance 0.09
Furthermore, we have identified a relatively large group of genes with parallel expression profiles to that of Tsc22d3 (Sgk, Klf15, Fzd2, Gpt2, Rhpn2, Nt5e, and Nfkbia), which may indicate morphine-induced co-regulation of these genes.
Gene_expression (expression) of Klf15 associated with morphine
3) Confidence 0.54 Published 2007 Journal Genome Biol Section Body Doc Link PMC2394777 Disease Relevance 0.12 Pain Relevance 0.51
Probes for Indian hedgehog (Ihh), Tissue inhibitor of matrix metalloproteinase 4 (Timp4), Cyclin-dependent kinase inhibitor 1C (Cdkn1c, p57), Integrin beta like 1 protein (Itgbl1), GC receptor (Nr3c1), Integrin beta 1 (Itgb1) and Kruppel-like factor 15 (Klf15) were assayed using the TaqMan® gene expression assays in accordance with the manufacturers directions.
Gene_expression (expression) of factor 15 associated with metalloproteinase
4) Confidence 0.50 Published 2007 Journal BMC Genomics Section Body Doc Link PMC1929075 Disease Relevance 0 Pain Relevance 0.09
Our study provides a rich dataset of cardiovascular-related phenotypes upon ?
Gene_expression (phenotypes) of cardiovascular-related
5) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2722085 Disease Relevance 0.53 Pain Relevance 0

General Comments

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