INT21079

From wiki-pain
Jump to: navigation, search
Context Info
Confidence 0.45
First Reported 1982
Last Reported 2008
Negated 2
Speculated 0
Reported most in Abstract
Documents 5
Total Number 5
Disease Relevance 0.40
Pain Relevance 0.65

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Pxk) nucleus (Pxk) molecular_function (Pxk)
cellular_component (Pxk) biological_process (Pxk) cytoplasm (Pxk)
Anatomy Link Frequency
jejunum 1
brain 1
skeletal muscle 1
ROLE 1
Pxk (Rattus norvegicus)
Pain Link Frequency Relevance Heat
agonist 2 100.00 Very High Very High Very High
opiate 1 99.80 Very High Very High Very High
tetrodotoxin 4 96.32 Very High Very High Very High
noradrenaline 5 90.96 High High
Clonidine 1 79.04 Quite High
nMDA receptor 3 19.76 Low Low
Glutamate receptor 3 16.24 Low Low
Central nervous system 13 5.00 Very Low Very Low Very Low
ischemia 4 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 165 84.00 Quite High
Death 31 71.96 Quite High
Hypoxia 6 69.92 Quite High
Neurodegenerative Disease 14 64.36 Quite High
Disease 17 5.00 Very Low Very Low Very Low
Stress 11 5.00 Very Low Very Low Very Low
Necrosis 8 5.00 Very Low Very Low Very Low
Pressure And Volume Under Development 8 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 4 5.00 Very Low Very Low Very Low
Injury 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
In the jejunum this opiate analogue affected neither basal or DOC-depressed Na-K-ATPase, nor mucosal cAMP.
Neg (nor) Regulation (affected) of Na-K-ATPase in jejunum associated with opiate
1) Confidence 0.45 Published 1984 Journal Naunyn Schmiedebergs Arch. Pharmacol. Section Abstract Doc Link 6328335 Disease Relevance 0 Pain Relevance 0.10
The number and activity of Na-K pump sites were unaffected by chronic elevation in [Ca]i or chronic depolarization.
Neg (unaffected) Regulation (unaffected) of Na-K
2) Confidence 0.45 Published 1989 Journal J. Cell. Physiol. Section Abstract Doc Link 2544613 Disease Relevance 0 Pain Relevance 0.25
The acute effects of veratridine on membrane potential (Em) and Na-K pump activity in cultured skeletal muscle were examined. 2.
Regulation (effects) of Na-K in skeletal muscle
3) Confidence 0.27 Published 1990 Journal Cell. Mol. Neurobiol. Section Abstract Doc Link 2163752 Disease Relevance 0 Pain Relevance 0.05
The effect of different adrenoceptor agonists on Na,K-ATPase activity and lipid peroxidation of rat brain homogenate was studied.
Regulation (effect) of Na,K-ATPase in brain associated with agonist
4) Confidence 0.24 Published 1982 Journal Biochem. Pharmacol. Section Abstract Doc Link 6127081 Disease Relevance 0 Pain Relevance 0.25
ROLE OF Na+/K+ ATPase
Regulation (ROLE) of Na+/K+ ATPase in ROLE
5) Confidence 0.02 Published 2008 Journal Current Neuropharmacology Section Body Doc Link PMC2647147 Disease Relevance 0.40 Pain Relevance 0

General Comments

This test has worked.

Personal tools
Namespaces

Variants
Actions
Navigation
Toolbox